Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model

Erik Widman, Elira Maksuti, Carolina Amador Carrascal, Matthew W Urban, Matilda Larsson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Our objective was to use shear wave elastography (SWE) to characterize the mechanical properties of an arterial wall with a simulated calcified plaque in an ex vivo setup. A small porcine aorta was used as a model for a human carotid artery and attached to a fixture while pressurized with a water column. The stiffness of the arterial wall and a simulated plaque were estimated using SWE. The mean arterial wall and plaque shear modulus varied from 42 ± 0 kPa to 100 ± 1 kPa and 81 ± 2 kPa to 174 ± 2 kPa respectively over a pressure range of 20-120 mmHg. The results show the ability of SWE to characterize the mechanical properties of an arterial wall with a simulated plaque and take steps toward an in vivo implementation for quantitative plaque assessment.

Original languageEnglish (US)
Title of host publication2015 IEEE International Ultrasonics Symposium, IUS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479981823
DOIs
StatePublished - Nov 13 2015
EventIEEE International Ultrasonics Symposium, IUS 2015 - Taipei, Taiwan, Province of China
Duration: Oct 21 2015Oct 24 2015

Other

OtherIEEE International Ultrasonics Symposium, IUS 2015
CountryTaiwan, Province of China
CityTaipei
Period10/21/1510/24/15

    Fingerprint

Keywords

  • Carotid Artery
  • Phase Velocity
  • Plaque Characterization
  • Shear Wave Elastography
  • Ultrasound

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Widman, E., Maksuti, E., Carrascal, C. A., Urban, M. W., & Larsson, M. (2015). Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model. In 2015 IEEE International Ultrasonics Symposium, IUS 2015 [7329503] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ULTSYM.2015.0120