Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model

Erik Widman; Elira Maksuti; Carolina Amador Carrascal; Matthew W Urban; Matilda Larsson

doi:10.1109/ULTSYM.2015.0120

Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model

Erik Widman, Elira Maksuti, Carolina Amador Carrascal, Matthew W Urban, Matilda Larsson

Physiology & Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Our objective was to use shear wave elastography (SWE) to characterize the mechanical properties of an arterial wall with a simulated calcified plaque in an ex vivo setup. A small porcine aorta was used as a model for a human carotid artery and attached to a fixture while pressurized with a water column. The stiffness of the arterial wall and a simulated plaque were estimated using SWE. The mean arterial wall and plaque shear modulus varied from 42 ± 0 kPa to 100 ± 1 kPa and 81 ± 2 kPa to 174 ± 2 kPa respectively over a pressure range of 20-120 mmHg. The results show the ability of SWE to characterize the mechanical properties of an arterial wall with a simulated plaque and take steps toward an in vivo implementation for quantitative plaque assessment.

Original language	English (US)
Title of host publication	2015 IEEE International Ultrasonics Symposium, IUS 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Print)	9781479981823
DOIs	https://doi.org/10.1109/ULTSYM.2015.0120
State	Published - Nov 13 2015
Event	IEEE International Ultrasonics Symposium, IUS 2015 - Taipei, Taiwan, Province of China Duration: Oct 21 2015 → Oct 24 2015

Other

Other	IEEE International Ultrasonics Symposium, IUS 2015
Country/Territory	Taiwan, Province of China
City	Taipei
Period	10/21/15 → 10/24/15

Keywords

Carotid Artery
Phase Velocity
Plaque Characterization
Shear Wave Elastography
Ultrasound

ASJC Scopus subject areas

Acoustics and Ultrasonics

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10.1109/ULTSYM.2015.0120

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Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model. / Widman, Erik; Maksuti, Elira; Carrascal, Carolina Amador et al.

2015 IEEE International Ultrasonics Symposium, IUS 2015. Institute of Electrical and Electronics Engineers Inc., 2015. 7329503.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Widman, E, Maksuti, E, Carrascal, CA, Urban, MW & Larsson, M 2015, Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model. in 2015 IEEE International Ultrasonics Symposium, IUS 2015., 7329503, Institute of Electrical and Electronics Engineers Inc., IEEE International Ultrasonics Symposium, IUS 2015, Taipei, Taiwan, Province of China, 10/21/15. https://doi.org/10.1109/ULTSYM.2015.0120

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title = "Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model",

abstract = "Our objective was to use shear wave elastography (SWE) to characterize the mechanical properties of an arterial wall with a simulated calcified plaque in an ex vivo setup. A small porcine aorta was used as a model for a human carotid artery and attached to a fixture while pressurized with a water column. The stiffness of the arterial wall and a simulated plaque were estimated using SWE. The mean arterial wall and plaque shear modulus varied from 42 ± 0 kPa to 100 ± 1 kPa and 81 ± 2 kPa to 174 ± 2 kPa respectively over a pressure range of 20-120 mmHg. The results show the ability of SWE to characterize the mechanical properties of an arterial wall with a simulated plaque and take steps toward an in vivo implementation for quantitative plaque assessment.",

keywords = "Carotid Artery, Phase Velocity, Plaque Characterization, Shear Wave Elastography, Ultrasound",

author = "Erik Widman and Elira Maksuti and Carrascal, {Carolina Amador} and Urban, {Matthew W} and Matilda Larsson",

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doi = "10.1109/ULTSYM.2015.0120",

language = "English (US)",

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booktitle = "2015 IEEE International Ultrasonics Symposium, IUS 2015",

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T1 - Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model

AU - Widman, Erik

AU - Maksuti, Elira

AU - Carrascal, Carolina Amador

AU - Urban, Matthew W

AU - Larsson, Matilda

PY - 2015/11/13

Y1 - 2015/11/13

N2 - Our objective was to use shear wave elastography (SWE) to characterize the mechanical properties of an arterial wall with a simulated calcified plaque in an ex vivo setup. A small porcine aorta was used as a model for a human carotid artery and attached to a fixture while pressurized with a water column. The stiffness of the arterial wall and a simulated plaque were estimated using SWE. The mean arterial wall and plaque shear modulus varied from 42 ± 0 kPa to 100 ± 1 kPa and 81 ± 2 kPa to 174 ± 2 kPa respectively over a pressure range of 20-120 mmHg. The results show the ability of SWE to characterize the mechanical properties of an arterial wall with a simulated plaque and take steps toward an in vivo implementation for quantitative plaque assessment.

AB - Our objective was to use shear wave elastography (SWE) to characterize the mechanical properties of an arterial wall with a simulated calcified plaque in an ex vivo setup. A small porcine aorta was used as a model for a human carotid artery and attached to a fixture while pressurized with a water column. The stiffness of the arterial wall and a simulated plaque were estimated using SWE. The mean arterial wall and plaque shear modulus varied from 42 ± 0 kPa to 100 ± 1 kPa and 81 ± 2 kPa to 174 ± 2 kPa respectively over a pressure range of 20-120 mmHg. The results show the ability of SWE to characterize the mechanical properties of an arterial wall with a simulated plaque and take steps toward an in vivo implementation for quantitative plaque assessment.

KW - Carotid Artery

KW - Phase Velocity

KW - Plaque Characterization

KW - Shear Wave Elastography

KW - Ultrasound

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BT - 2015 IEEE International Ultrasonics Symposium, IUS 2015

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - IEEE International Ultrasonics Symposium, IUS 2015

Y2 - 21 October 2015 through 24 October 2015

ER -

Evaluating arterial and plaque elasticity with shear wave elastography in an ex vivo porcine model

Abstract

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Keywords

ASJC Scopus subject areas

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