EUS-guided ethanol lavage does not reliably ablate pancreatic cystic neoplasms (with video)

Victoria Gómez, Naoki Takahashi, Michael J. Levy, Kiaran Patrick McGee, Andrea Jones, Yajue Huang, Suresh T Chari, Jonathan E. Clain, Ferga C. Gleeson, Randall K. Pearson, Bret Thomas Petersen, Elizabeth Rajan, Santhi Swaroop Vege, Mark Topazian

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Background: The true efficacy of EUS-guided ethanol lavage (EEL) of pancreatic cystic neoplasms is unclear. This study aimed to assess long-term outcomes and adverse events of EEL by using a standardized protocol. Methods: Single-center, prospective, pilot study in which participants with suspected mucinous cyst neoplasms or branch duct intraductal papillary mucinous neoplasms ≥1 cm in maximum diameter underwent EEL with 80% ethanol. Follow-up cross-sectional imaging was obtained to assess for changes in cyst volume. Results: Twenty-three patients underwent EEL (57% male, mean age 70 years). Mean duration of follow-up was 40 months (range 9-82 months). Mean calculated final concentration of ethanol achieved in treated cysts was 50% (range 0%-79%). Complete resolution of pancreatic cystic neoplasms occurred in 2 participants (9%). When stratified into those participants who achieved ≥80% versus

Original languageEnglish (US)
JournalGastrointestinal Endoscopy
DOIs
StateAccepted/In press - Jun 16 2015

ASJC Scopus subject areas

  • Gastroenterology
  • Radiology Nuclear Medicine and imaging

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    Gómez, V., Takahashi, N., Levy, M. J., McGee, K. P., Jones, A., Huang, Y., Chari, S. T., Clain, J. E., Gleeson, F. C., Pearson, R. K., Petersen, B. T., Rajan, E., Vege, S. S., & Topazian, M. (Accepted/In press). EUS-guided ethanol lavage does not reliably ablate pancreatic cystic neoplasms (with video). Gastrointestinal Endoscopy. https://doi.org/10.1016/j.gie.2015.08.069