Etiologic considerations in superior vena cava syndrome

J. M. Parish, R. F. Marschke, D. E. Dines, R. E. Lee

Research output: Contribution to journalArticle

275 Citations (Scopus)

Abstract

The Mayo Clinic experience with superior vena cava obstruction during the last 20 years was reviewed. The superior of superir vena cava obstruction is often made at the bedside. Typical symptoms include suffusion, dyspnea, cough, and, less commonly, pain, syncope, dysphagia, and hemoptysis. The most important physical findings are the increased collateral veins covering the anterior chest wall and the dilated neck veins with edema of the face, arms, and chest. The chest x-ray film usually shows widening of the superior mediastinum. Of our 86 cases of superior vena cava obstruction, 67 (78%) were due to malignancy and 19 (22%) to benign causes. The cause of obstruction is usually established by bronchoscopy, open lung biopsy, or biopsy of the superficial lymph node. Radiotherapy remains the standard approach for the treatment of superior vena cava obstruction due to malignant disease. It is of particular interest to note that of the six benign cases resulting from thrombosis of the superior vena cava, three were due to the use of central venous catheters. Physicians should be aware of this association.

Original languageEnglish (US)
Pages (from-to)407-413
Number of pages7
JournalMayo Clinic Proceedings
Volume56
Issue number7
StatePublished - 1981

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Superior Vena Cava Syndrome
Veins
Thorax
Biopsy
Hemoptysis
Central Venous Catheters
Syncope
Mediastinum
Thoracic Wall
Bronchoscopy
Motion Pictures
Deglutition Disorders
Cough
Dyspnea
Edema
Arm
Neck
Radiotherapy
Lymph Nodes
X-Rays

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Parish, J. M., Marschke, R. F., Dines, D. E., & Lee, R. E. (1981). Etiologic considerations in superior vena cava syndrome. Mayo Clinic Proceedings, 56(7), 407-413.

Etiologic considerations in superior vena cava syndrome. / Parish, J. M.; Marschke, R. F.; Dines, D. E.; Lee, R. E.

In: Mayo Clinic Proceedings, Vol. 56, No. 7, 1981, p. 407-413.

Research output: Contribution to journalArticle

Parish, JM, Marschke, RF, Dines, DE & Lee, RE 1981, 'Etiologic considerations in superior vena cava syndrome', Mayo Clinic Proceedings, vol. 56, no. 7, pp. 407-413.
Parish JM, Marschke RF, Dines DE, Lee RE. Etiologic considerations in superior vena cava syndrome. Mayo Clinic Proceedings. 1981;56(7):407-413.
Parish, J. M. ; Marschke, R. F. ; Dines, D. E. ; Lee, R. E. / Etiologic considerations in superior vena cava syndrome. In: Mayo Clinic Proceedings. 1981 ; Vol. 56, No. 7. pp. 407-413.
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