Ethical Challenges in COVID-19 Biospecimen Research: Perspectives From Institutional Review Board Members and Bioethicists

Maria I. Lapid; Karen M. Meagher; Hannah C. Giunta; Bart L. Clarke; Yves Ouellette; Tamyra L. Armbrust; Richard R. Sharp; R. Scott Wright

doi:10.1016/j.mayocp.2020.10.021

Ethical Challenges in COVID-19 Biospecimen Research: Perspectives From Institutional Review Board Members and Bioethicists

Maria I. Lapid, Karen M. Meagher, Hannah C. Giunta, Bart L. Clarke, Yves Ouellette, Tamyra L. Armbrust, Richard R. Sharp, R. Scott Wright

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Biospecimen research is a prominent investigative strategy that aims to provide novel insights into coronavirus disease 2019 (COVID-19), inform clinical trials, and develop effective, life-saving treatments. However, COVID-19 biospecimen research raises accompanying ethical concerns and practical challenges for investigators and participants. In this special article, we discuss the ethical issues that are associated with autonomy, beneficence, and justice in COVID-19 biospecimen research and describe strategies to manage the practical challenges, with an emphasis on protecting the rights and welfare of human research participants during a pandemic response. Appropriate institutional review board oversight and bioethics guidance for COVID-19 biospecimen research must maintain their focus on protecting the rights and welfare of research participants, despite the urgent need for more knowledge about the virus and the threat it poses to communities and nations.

Original language	English (US)
Pages (from-to)	165-173
Number of pages	9
Journal	Mayo Clinic proceedings
Volume	96
Issue number	1
DOIs	https://doi.org/10.1016/j.mayocp.2020.10.021
State	Published - Jan 2021

ASJC Scopus subject areas

General Medicine

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10.1016/j.mayocp.2020.10.021

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title = "Ethical Challenges in COVID-19 Biospecimen Research: Perspectives From Institutional Review Board Members and Bioethicists",

abstract = "Biospecimen research is a prominent investigative strategy that aims to provide novel insights into coronavirus disease 2019 (COVID-19), inform clinical trials, and develop effective, life-saving treatments. However, COVID-19 biospecimen research raises accompanying ethical concerns and practical challenges for investigators and participants. In this special article, we discuss the ethical issues that are associated with autonomy, beneficence, and justice in COVID-19 biospecimen research and describe strategies to manage the practical challenges, with an emphasis on protecting the rights and welfare of human research participants during a pandemic response. Appropriate institutional review board oversight and bioethics guidance for COVID-19 biospecimen research must maintain their focus on protecting the rights and welfare of research participants, despite the urgent need for more knowledge about the virus and the threat it poses to communities and nations.",

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AU - Clarke, Bart L.

AU - Ouellette, Yves

AU - Armbrust, Tamyra L.

AU - Sharp, Richard R.

AU - Wright, R. Scott

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Ethical Challenges in COVID-19 Biospecimen Research: Perspectives From Institutional Review Board Members and Bioethicists

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