TY - JOUR
T1 - Ethanol ablation of neck metastases from differentiated thyroid carcinoma
AU - Paz-Fumagalli, Ricardo
AU - Li, Xi
AU - Smallridge, Robert C.
N1 - Publisher Copyright:
© 2019 Georg Thieme Verlag. All rights reserved.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019
Y1 - 2019
N2 - Differentiated thyroid cancer often metastasizes to cervical lymph nodes, characteristically with slow growth rate and low-level aggressiveness. Cervical lymph node resection is the treatment of choice, but ethanol ablation offers a therapeutic option for patients with few nodes unresponsive to radioiodine therapy and who are poor surgical candidates. The ethanol ablation procedure is minimally invasive, guided sonographically, easily and safely repeated, and easily implemented with minimal technology and cost. Transient nerve injury is infrequent and virtually the only important complication. Current experience indicates that ethanol ablation has the safest therapeutic profile compared to surgery and thermal ablation, and the effectiveness is comparable to thermal ablation and approaches that of surgery. Well-designed clinical trials are lacking.
AB - Differentiated thyroid cancer often metastasizes to cervical lymph nodes, characteristically with slow growth rate and low-level aggressiveness. Cervical lymph node resection is the treatment of choice, but ethanol ablation offers a therapeutic option for patients with few nodes unresponsive to radioiodine therapy and who are poor surgical candidates. The ethanol ablation procedure is minimally invasive, guided sonographically, easily and safely repeated, and easily implemented with minimal technology and cost. Transient nerve injury is infrequent and virtually the only important complication. Current experience indicates that ethanol ablation has the safest therapeutic profile compared to surgery and thermal ablation, and the effectiveness is comparable to thermal ablation and approaches that of surgery. Well-designed clinical trials are lacking.
KW - ethanol
KW - lymph node metastasis
KW - nerve injury
KW - thyroid carcinoma
KW - ultrasound
UR - http://www.scopus.com/inward/record.url?scp=85076015040&partnerID=8YFLogxK
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U2 - 10.1055/s-0039-1696651
DO - 10.1055/s-0039-1696651
M3 - Article
AN - SCOPUS:85076015040
VL - 36
SP - 381
EP - 385
JO - Seminars in Interventional Radiology
JF - Seminars in Interventional Radiology
SN - 0739-9529
IS - 5
ER -