Abstract
It is well established that E2 and TGFβ have major biological effects in multiple tissues, including bone. The signaling pathways through which these two factors elicit their effects are well documented. However, the interaction between these two pathways and the potential consequences of cross-talk between E2 and TGFβ continue to be elucidated. In this prospectus, we present known and potential roles of TIEC, Runx2, and other transcription factors as important mediators of signaling between these two pathways.
Original language | English (US) |
---|---|
Pages (from-to) | 383-392 |
Number of pages | 10 |
Journal | Journal of cellular biochemistry |
Volume | 103 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1 2008 |
Keywords
- Bone
- Estrogen
- Osteoblast
- Osteoclast
- Runx2
- TGFβ
- TIEG
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Cell Biology