TY - JOUR
T1 - Esthesioneuroblastoma
T2 - Treatment of skull-base recurrence
AU - Jackson, Ian T.
AU - Somers, Peter
AU - Marsh, W. Richard
PY - 1985/8
Y1 - 1985/8
N2 - Thirty-nine patients with esthcsioncuroblastoma arc reviewed. The presentation of the tumor, symptomatology. investigation, and treatment are discussed. A recommended treatment regimen is outlined. Histologic typing is valueless in predicting tumor behavior. An illustrative and difficult case of recurrent base of skull esthcsioncuroblastoma is presented. The resection performed is described, and the problem of extradural oropharyngeal communication is discussed. The solution was to use a temporalis and galcal frontalis flap. Reconstruction was with an external and intraoral prosthesis. Optimal treatment in a fresh lesion is radical surgery with or without radiation therapy. Esihesioneuroblasioma is a rare and often misdiagnosed malignant tumor of the olfactory epithelium.1 Originally described by Bergen et al. in 1924 as “esthesioncuroepithelioma olfactif,”2 it was introduced into the North American literature by Schall and Lineback3 in 1951. Since then, fewer than 200 cases have been collected4. The various terms used to describe it—olfactory esihesioneuroblasioma, eslhesioneurocytoma, and olfactory neuroblastoma—all denote origin from the neural crest. The sensory nerves of smell are short bundles of fibers that originate in the olfactory bulb and pass through the cribriform plate to the olfactory area of the nasal mucosa. This mucosa is located in the most superior part of both nasal fossae.5 Thus the usual primary sites of occurrence include the superior nasal cavity or nasal septum, the turbinates, the ethmoid, or the cribriform plate, although an extranasal site of origin has been suggested. 6-101 Symptoms are usually progressive and range from nasal obstruction or cpistaxis to diplopia, ocular pain, and headaches in the more advanced disease state. This paper reviews the Mayo Clinic experience from 1950 to 1983 and presents an illustrative case of recurrent csthesioneuroblastoma and its treatment, emphasizing particularly the problems associated with removal of a tumor in the anterior cranial base area.
AB - Thirty-nine patients with esthcsioncuroblastoma arc reviewed. The presentation of the tumor, symptomatology. investigation, and treatment are discussed. A recommended treatment regimen is outlined. Histologic typing is valueless in predicting tumor behavior. An illustrative and difficult case of recurrent base of skull esthcsioncuroblastoma is presented. The resection performed is described, and the problem of extradural oropharyngeal communication is discussed. The solution was to use a temporalis and galcal frontalis flap. Reconstruction was with an external and intraoral prosthesis. Optimal treatment in a fresh lesion is radical surgery with or without radiation therapy. Esihesioneuroblasioma is a rare and often misdiagnosed malignant tumor of the olfactory epithelium.1 Originally described by Bergen et al. in 1924 as “esthesioncuroepithelioma olfactif,”2 it was introduced into the North American literature by Schall and Lineback3 in 1951. Since then, fewer than 200 cases have been collected4. The various terms used to describe it—olfactory esihesioneuroblasioma, eslhesioneurocytoma, and olfactory neuroblastoma—all denote origin from the neural crest. The sensory nerves of smell are short bundles of fibers that originate in the olfactory bulb and pass through the cribriform plate to the olfactory area of the nasal mucosa. This mucosa is located in the most superior part of both nasal fossae.5 Thus the usual primary sites of occurrence include the superior nasal cavity or nasal septum, the turbinates, the ethmoid, or the cribriform plate, although an extranasal site of origin has been suggested. 6-101 Symptoms are usually progressive and range from nasal obstruction or cpistaxis to diplopia, ocular pain, and headaches in the more advanced disease state. This paper reviews the Mayo Clinic experience from 1950 to 1983 and presents an illustrative case of recurrent csthesioneuroblastoma and its treatment, emphasizing particularly the problems associated with removal of a tumor in the anterior cranial base area.
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U2 - 10.1097/00006534-198508000-00003
DO - 10.1097/00006534-198508000-00003
M3 - Article
C2 - 4023092
AN - SCOPUS:0022005527
SN - 0032-1052
VL - 76
SP - 195
EP - 200
JO - Plastic and reconstructive surgery
JF - Plastic and reconstructive surgery
IS - 2
ER -