Establishment of a persistent mutant of canine distemper virus

Kiyoko Iwatsuki; Yasuhiro Ikeda; Kenjiro Ohashi; Kazuya Nakamura; Chieko Kai

doi:10.1016/S1286-4579(99)80516-4

Establishment of a persistent mutant of canine distemper virus

Kiyoko Iwatsuki, Yasuhiro Ikeda, Kenjiro Ohashi, Kazuya Nakamura, Chieko Kai

Molecular Medicine

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

We produced a B95a lymphoid cell line persistently infected with canine distemper virus (CDV), in which virus-specific antigens were present in nearly 100% of cells without causing cytopathic effect. The virus recovered from this cell line was able to infect fresh B95a cells persistently, indicating that a persistent CDV was established.

Original language	English (US)
Pages (from-to)	987-991
Number of pages	5
Journal	Microbes and Infection
Volume	1
Issue number	12
DOIs	https://doi.org/10.1016/S1286-4579(99)80516-4
State	Published - Oct 1999

Keywords

B95a cells
CDV
Persistent infection

ASJC Scopus subject areas

Microbiology
Immunology
Infectious Diseases

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10.1016/S1286-4579(99)80516-4

Cite this

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title = "Establishment of a persistent mutant of canine distemper virus",

abstract = "We produced a B95a lymphoid cell line persistently infected with canine distemper virus (CDV), in which virus-specific antigens were present in nearly 100% of cells without causing cytopathic effect. The virus recovered from this cell line was able to infect fresh B95a cells persistently, indicating that a persistent CDV was established.",

keywords = "B95a cells, CDV, Persistent infection",

author = "Kiyoko Iwatsuki and Yasuhiro Ikeda and Kenjiro Ohashi and Kazuya Nakamura and Chieko Kai",

note = "Funding Information: This study was supported by Grants-in-Aid from the Ministry of Education, Science, Culture and Sports, Japan, and by a grant for Program for Promotion of Basic Research Activities for Innovative Biosciences, Japan. K. Iwatsuki is supported by Research Fellowships of Japan Society for the Promotion of Science for Young Scientists.",

year = "1999",

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doi = "10.1016/S1286-4579(99)80516-4",

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T1 - Establishment of a persistent mutant of canine distemper virus

AU - Iwatsuki, Kiyoko

AU - Ikeda, Yasuhiro

AU - Ohashi, Kenjiro

AU - Nakamura, Kazuya

AU - Kai, Chieko

N1 - Funding Information: This study was supported by Grants-in-Aid from the Ministry of Education, Science, Culture and Sports, Japan, and by a grant for Program for Promotion of Basic Research Activities for Innovative Biosciences, Japan. K. Iwatsuki is supported by Research Fellowships of Japan Society for the Promotion of Science for Young Scientists.

PY - 1999/10

Y1 - 1999/10

N2 - We produced a B95a lymphoid cell line persistently infected with canine distemper virus (CDV), in which virus-specific antigens were present in nearly 100% of cells without causing cytopathic effect. The virus recovered from this cell line was able to infect fresh B95a cells persistently, indicating that a persistent CDV was established.

AB - We produced a B95a lymphoid cell line persistently infected with canine distemper virus (CDV), in which virus-specific antigens were present in nearly 100% of cells without causing cytopathic effect. The virus recovered from this cell line was able to infect fresh B95a cells persistently, indicating that a persistent CDV was established.

KW - B95a cells

KW - CDV

KW - Persistent infection

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U2 - 10.1016/S1286-4579(99)80516-4

DO - 10.1016/S1286-4579(99)80516-4

M3 - Review article

C2 - 10617930

AN - SCOPUS:0032717012

SN - 1286-4579

VL - 1

SP - 987

EP - 991

JO - Microbes and Infection

JF - Microbes and Infection

IS - 12

ER -

Establishment of a persistent mutant of canine distemper virus

Abstract

Keywords

ASJC Scopus subject areas

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