Abstract
Introduction: Depression and neuropsychiatric disorders in individuals with essential tremor (ET) are not well characterized in the literature. Methods: We compared 104 ET subjects with 481 non-ET controls involved in the Arizona Study of Aging and Neurodegenerative Disorders. An analysis of baseline depression scales and neuropsychiatric inventory (NPI) was done between the two groups. Additionally, comparisons were made within the ET group based on tremor severity, duration of tremor, and age of onset. Results: There were no significant differences between the ET and non-ET groups. There were no significant differences in the ET group above and below the median tremor duration. Additionally, no differences were found in the ET group based on objective measures of tremor severity, age of onset, or those with subjectively distressing tremor compared with those without. Conclusion: There were no significant differences in depressive symptoms between ET and non-ET groups. Furthermore, no correlation was found between depressive symptoms in ET groups based on tremor severity, duration, or age of onset.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 838-842 |
| Number of pages | 5 |
| Journal | Movement Disorders Clinical Practice |
| Volume | 4 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 1 2017 |
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Keywords
- cognitive
- depression
- essential tremor
- tremor
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
Cite this
Essential Tremor and Depression. / Aslam, Sana; Zhang, Nan; Adler, Charles Howard; Caviness, John Nathaniel; Driver-Dunckley, Erika M; Mehta, Shyamal; Sabbagh, Marwan N.; Belden, Christine; Zamrini, Edward; Beach, Thomas G.; Shill, Holly A.
In: Movement Disorders Clinical Practice, Vol. 4, No. 6, 01.11.2017, p. 838-842.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Essential Tremor and Depression
AU - Aslam, Sana
AU - Zhang, Nan
AU - Adler, Charles Howard
AU - Caviness, John Nathaniel
AU - Driver-Dunckley, Erika M
AU - Mehta, Shyamal
AU - Sabbagh, Marwan N.
AU - Belden, Christine
AU - Zamrini, Edward
AU - Beach, Thomas G.
AU - Shill, Holly A.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Introduction: Depression and neuropsychiatric disorders in individuals with essential tremor (ET) are not well characterized in the literature. Methods: We compared 104 ET subjects with 481 non-ET controls involved in the Arizona Study of Aging and Neurodegenerative Disorders. An analysis of baseline depression scales and neuropsychiatric inventory (NPI) was done between the two groups. Additionally, comparisons were made within the ET group based on tremor severity, duration of tremor, and age of onset. Results: There were no significant differences between the ET and non-ET groups. There were no significant differences in the ET group above and below the median tremor duration. Additionally, no differences were found in the ET group based on objective measures of tremor severity, age of onset, or those with subjectively distressing tremor compared with those without. Conclusion: There were no significant differences in depressive symptoms between ET and non-ET groups. Furthermore, no correlation was found between depressive symptoms in ET groups based on tremor severity, duration, or age of onset.
AB - Introduction: Depression and neuropsychiatric disorders in individuals with essential tremor (ET) are not well characterized in the literature. Methods: We compared 104 ET subjects with 481 non-ET controls involved in the Arizona Study of Aging and Neurodegenerative Disorders. An analysis of baseline depression scales and neuropsychiatric inventory (NPI) was done between the two groups. Additionally, comparisons were made within the ET group based on tremor severity, duration of tremor, and age of onset. Results: There were no significant differences between the ET and non-ET groups. There were no significant differences in the ET group above and below the median tremor duration. Additionally, no differences were found in the ET group based on objective measures of tremor severity, age of onset, or those with subjectively distressing tremor compared with those without. Conclusion: There were no significant differences in depressive symptoms between ET and non-ET groups. Furthermore, no correlation was found between depressive symptoms in ET groups based on tremor severity, duration, or age of onset.
KW - cognitive
KW - depression
KW - essential tremor
KW - tremor
UR - http://www.scopus.com/inward/record.url?scp=85058850468&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85058850468&partnerID=8YFLogxK
U2 - 10.1002/mdc3.12530
DO - 10.1002/mdc3.12530
M3 - Article
AN - SCOPUS:85058850468
VL - 4
SP - 838
EP - 842
JO - Movement Disorders Clinical Practice
JF - Movement Disorders Clinical Practice
SN - 2330-1619
IS - 6
ER -