Esophageal lichen planus: The Mayo Clinic experience

G. C. Harewood, Joseph A Murray, A. J. Cameron

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Lichen planus (LP) is an inflammatory papulosquamous disease which may affect the squamous epithelium of the esophagus. We reviewed six patients with esophageal lichen planus (ELP) seen at Mayo Clinic Rochester between 1984 and 1998. The presenting symptoms were dysphagia (in all six patients) and odynophagia (two patients). Cervical esophageal strictures were seen in four patients; average number of esophageal dilatations required was 15 (range, 10-18). Esophageal biopsies demonstrated the classical histologic findings of ELP in two patients, and a lymphocytic infiltrate in the other four. Concomitant lichen planus (LP) was seen at other sites in five patients: all five had oral LP preceeded by ELP symptoms in all five; three had genital LP preceeded by ELP symptoms in all three; two had dermal LP, preceeded by ELP symptoms in one. Proton pump inhibitors were tried unsuccessfully in all patients. Four patients were started on systemic steroid medication; three had resolution of symptoms within 1 month.

Original languageEnglish (US)
Pages (from-to)309-311
Number of pages3
JournalDiseases of the Esophagus
Volume12
Issue number4
DOIs
StatePublished - 1999

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Lichen Planus
Oral Lichen Planus
Esophageal Stenosis
Proton Pump Inhibitors
Deglutition Disorders
Esophagus
Dilatation
Epithelium
Steroids
Biopsy
Skin

ASJC Scopus subject areas

  • Gastroenterology

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Esophageal lichen planus : The Mayo Clinic experience. / Harewood, G. C.; Murray, Joseph A; Cameron, A. J.

In: Diseases of the Esophagus, Vol. 12, No. 4, 1999, p. 309-311.

Research output: Contribution to journalArticle

Harewood, G. C. ; Murray, Joseph A ; Cameron, A. J. / Esophageal lichen planus : The Mayo Clinic experience. In: Diseases of the Esophagus. 1999 ; Vol. 12, No. 4. pp. 309-311.
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