Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma

Karthik Ravi, D. Chamil Codipilly, Dharma Sunjaya, Hongfei Fang, Amindra S. Arora, David A Katzka

Research output: Contribution to journalShort survey

2 Scopus citations

Abstract

Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.

Original languageEnglish (US)
Pages (from-to)1902-1903.e1
JournalClinical Gastroenterology and Hepatology
Volume17
Issue number9
DOIs
StatePublished - Aug 1 2019

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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