Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma

Karthik Ravi, D. Chamil Codipilly, Dharma Sunjaya, Hongfei Fang, Amindra S. Arora, David A Katzka

Research output: Contribution to journalShort survey

Abstract

Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.

Original languageEnglish (US)
Pages (from-to)1902-1903.e1
JournalClinical Gastroenterology and Hepatology
Volume17
Issue number9
DOIs
StatePublished - Aug 1 2019

Fingerprint

Lichen Planus
Squamous Cell Carcinoma
Esophageal Neoplasms
Keratinocytes
Inflammation
T-Lymphocytes
Population

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma. / Ravi, Karthik; Codipilly, D. Chamil; Sunjaya, Dharma; Fang, Hongfei; Arora, Amindra S.; Katzka, David A.

In: Clinical Gastroenterology and Hepatology, Vol. 17, No. 9, 01.08.2019, p. 1902-1903.e1.

Research output: Contribution to journalShort survey

Ravi, Karthik ; Codipilly, D. Chamil ; Sunjaya, Dharma ; Fang, Hongfei ; Arora, Amindra S. ; Katzka, David A. / Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma. In: Clinical Gastroenterology and Hepatology. 2019 ; Vol. 17, No. 9. pp. 1902-1903.e1.
@article{3d05f93375414129965c35df3d0b9ebe,
title = "Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma",
abstract = "Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.",
author = "Karthik Ravi and Codipilly, {D. Chamil} and Dharma Sunjaya and Hongfei Fang and Arora, {Amindra S.} and Katzka, {David A}",
year = "2019",
month = "8",
day = "1",
doi = "10.1016/j.cgh.2018.10.018",
language = "English (US)",
volume = "17",
pages = "1902--1903.e1",
journal = "Clinical Gastroenterology and Hepatology",
issn = "1542-3565",
publisher = "W.B. Saunders Ltd",
number = "9",

}

TY - JOUR

T1 - Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma

AU - Ravi, Karthik

AU - Codipilly, D. Chamil

AU - Sunjaya, Dharma

AU - Fang, Hongfei

AU - Arora, Amindra S.

AU - Katzka, David A

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.

AB - Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.

UR - http://www.scopus.com/inward/record.url?scp=85069580288&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85069580288&partnerID=8YFLogxK

U2 - 10.1016/j.cgh.2018.10.018

DO - 10.1016/j.cgh.2018.10.018

M3 - Short survey

VL - 17

SP - 1902-1903.e1

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

SN - 1542-3565

IS - 9

ER -