Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma

Karthik Ravi; D. Chamil Codipilly; Dharma Sunjaya; Hongfei Fang; Amindra S. Arora; David A Katzka

doi:10.1016/j.cgh.2018.10.018

Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma

Karthik Ravi, D. Chamil Codipilly, Dharma Sunjaya, Hongfei Fang, Amindra S. Arora, David A Katzka

Gastroenterology and Hepatology

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.^1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.^4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.

Original language	English (US)
Pages (from-to)	1902-1903.e1
Journal	Clinical Gastroenterology and Hepatology
Volume	17
Issue number	9
DOIs	https://doi.org/10.1016/j.cgh.2018.10.018
State	Published - Aug 1 2019

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.1016/j.cgh.2018.10.018

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@article{3d05f93375414129965c35df3d0b9ebe,

title = "Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma",

abstract = "Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.",

author = "Karthik Ravi and Codipilly, {D. Chamil} and Dharma Sunjaya and Hongfei Fang and Arora, {Amindra S.} and Katzka, {David A}",

year = "2019",

month = aug,

day = "1",

doi = "10.1016/j.cgh.2018.10.018",

language = "English (US)",

volume = "17",

pages = "1902--1903.e1",

journal = "Clinical Gastroenterology and Hepatology",

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number = "9",

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TY - JOUR

T1 - Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma

AU - Ravi, Karthik

AU - Codipilly, D. Chamil

AU - Sunjaya, Dharma

AU - Fang, Hongfei

AU - Arora, Amindra S.

AU - Katzka, David A

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.

AB - Esophageal lichen planus (ELP) is a chronic inflammatory process characterized by apoptotic activity of cytotoxic CD8+ T cells on basal keratinocytes as well as regulatory and helper T cells.1–3 Due to chronic inflammation, malignant transformation may be a concern and has been documented in case reports.4,5 We describe the occurrence of esophageal cancer in ELP patients from a large tertiary patient population.

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UR - http://www.scopus.com/inward/citedby.url?scp=85069580288&partnerID=8YFLogxK

U2 - 10.1016/j.cgh.2018.10.018

DO - 10.1016/j.cgh.2018.10.018

M3 - Short survey

C2 - 30342260

AN - SCOPUS:85069580288

SN - 1542-3565

VL - 17

SP - 1902-1903.e1

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

IS - 9

ER -

Esophageal Lichen Planus Is Associated With a Significant Increase in Risk of Squamous Cell Carcinoma

Abstract

ASJC Scopus subject areas

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