Esophageal Epidermoid Metaplasia: Clinical Characteristics and Risk of Esophageal Squamous Neoplasia

Amrit K. Kamboj; Ying Y. Gibbens; Catherine E. Hagen; Kenneth K. Wang; Prasad G. Iyer; David A. Katzka

doi:10.14309/ajg.0000000000001225

Esophageal Epidermoid Metaplasia: Clinical Characteristics and Risk of Esophageal Squamous Neoplasia

Amrit K. Kamboj, Ying Y. Gibbens, Catherine E. Hagen, Kenneth K. Wang, Prasad G. Iyer, David A. Katzka

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

Abstract

INTRODUCTION:Esophageal epidermoid metaplasia (EEM) is a rare disease.METHODS:Patients with EEM diagnosed between 2014 and 2020 were reviewed.RESULTS:Forty EEM cases were identified. EEM occurred in 9 (23%) patients before, concordant, or after esophageal squamous cell carcinoma (ESCC). EEM was associated with previous esophageal lichen planus in 5 patients, Barrett's esophagus 7, and esophageal adenocarcinoma 1. EEM was focal in 28 (70%) or diffuse in 12 (30%) and not detected in 45% on recent previous endoscopy.DISCUSSION:EEM is a premalignant underrecognized condition associated with multiple conditions. Close follow-up or endoscopic treatment may be warranted because of its ESCC association.

Original language	English (US)
Pages (from-to)	1533-1536
Number of pages	4
Journal	American Journal of Gastroenterology
Volume	116
Issue number	7
DOIs	https://doi.org/10.14309/ajg.0000000000001225
State	Published - Jul 1 2021

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.14309/ajg.0000000000001225

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title = "Esophageal Epidermoid Metaplasia: Clinical Characteristics and Risk of Esophageal Squamous Neoplasia",

abstract = "INTRODUCTION:Esophageal epidermoid metaplasia (EEM) is a rare disease.METHODS:Patients with EEM diagnosed between 2014 and 2020 were reviewed.RESULTS:Forty EEM cases were identified. EEM occurred in 9 (23%) patients before, concordant, or after esophageal squamous cell carcinoma (ESCC). EEM was associated with previous esophageal lichen planus in 5 patients, Barrett's esophagus 7, and esophageal adenocarcinoma 1. EEM was focal in 28 (70%) or diffuse in 12 (30%) and not detected in 45% on recent previous endoscopy.DISCUSSION:EEM is a premalignant underrecognized condition associated with multiple conditions. Close follow-up or endoscopic treatment may be warranted because of its ESCC association.",

author = "Kamboj, {Amrit K.} and Gibbens, {Ying Y.} and Hagen, {Catherine E.} and Wang, {Kenneth K.} and Iyer, {Prasad G.} and Katzka, {David A.}",

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T1 - Esophageal Epidermoid Metaplasia

T2 - Clinical Characteristics and Risk of Esophageal Squamous Neoplasia

AU - Kamboj, Amrit K.

AU - Gibbens, Ying Y.

AU - Hagen, Catherine E.

AU - Wang, Kenneth K.

AU - Iyer, Prasad G.

AU - Katzka, David A.

PY - 2021/7/1

Y1 - 2021/7/1

N2 - INTRODUCTION:Esophageal epidermoid metaplasia (EEM) is a rare disease.METHODS:Patients with EEM diagnosed between 2014 and 2020 were reviewed.RESULTS:Forty EEM cases were identified. EEM occurred in 9 (23%) patients before, concordant, or after esophageal squamous cell carcinoma (ESCC). EEM was associated with previous esophageal lichen planus in 5 patients, Barrett's esophagus 7, and esophageal adenocarcinoma 1. EEM was focal in 28 (70%) or diffuse in 12 (30%) and not detected in 45% on recent previous endoscopy.DISCUSSION:EEM is a premalignant underrecognized condition associated with multiple conditions. Close follow-up or endoscopic treatment may be warranted because of its ESCC association.

AB - INTRODUCTION:Esophageal epidermoid metaplasia (EEM) is a rare disease.METHODS:Patients with EEM diagnosed between 2014 and 2020 were reviewed.RESULTS:Forty EEM cases were identified. EEM occurred in 9 (23%) patients before, concordant, or after esophageal squamous cell carcinoma (ESCC). EEM was associated with previous esophageal lichen planus in 5 patients, Barrett's esophagus 7, and esophageal adenocarcinoma 1. EEM was focal in 28 (70%) or diffuse in 12 (30%) and not detected in 45% on recent previous endoscopy.DISCUSSION:EEM is a premalignant underrecognized condition associated with multiple conditions. Close follow-up or endoscopic treatment may be warranted because of its ESCC association.

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Esophageal Epidermoid Metaplasia: Clinical Characteristics and Risk of Esophageal Squamous Neoplasia

Abstract

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