Erosive arthropathy: Clinical variance in lupus erythematosus and associated with anti-CCP case series and review of the literature

Jose Bernardo Martinez, Jenny Soraida Valero, Alain J. Bautista, Jose Felix Restrepo, Eric L. Matteson, Frederico Rondon, Antonio Iglesias-Gamarra

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Objective: To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies. Methods: Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies. Results: The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor. Conclusion: Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease.

Original languageEnglish (US)
Pages (from-to)47-53
Number of pages7
JournalClinical and experimental rheumatology
Volume25
Issue number1
StatePublished - Jan 1 2007

Keywords

  • Anti-CCP
  • Erosive arthritis
  • Rhupus
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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    Martinez, J. B., Valero, J. S., Bautista, A. J., Restrepo, J. F., Matteson, E. L., Rondon, F., & Iglesias-Gamarra, A. (2007). Erosive arthropathy: Clinical variance in lupus erythematosus and associated with anti-CCP case series and review of the literature. Clinical and experimental rheumatology, 25(1), 47-53.