@article{003065321b4e47ad8393a32c5a7da930,
title = "Erectile dysfunction in men with psoriatic arthritis: A population-based cohort study",
abstract = "Objective. To define the incidence of erectile dysfunction (ED) in a population-based cohort of men with psoriatic arthritis (PsA). Methods. Data pertaining to demographics, ED, and potential confounding diagnosis were extracted from a comprehensive medical record system for a population-based cohort of men with PsA and an age-matched male comparator cohort. Cumulative incidence of ED adjusted for competing risk of death was compared between the 2 cohorts. Results. There were 128 age-matched pairs of men with PsA and without PsA in the described cohorts. At baseline, there was a 7% prevalence of ED in men with PsA prior to diagnosis compared to a 3% prevalence of ED in the comparator cohort (P = 0.16). After PsA diagnosis/index date, diagnosis with PsA was associated with an increased risk of ED (age-adjusted HR 1.45, 95% CI 0.79–2.68), but this association did not reach statistical significance. This was based on 24 cases of ED in the men with PsA and 18 cases within the comparator cohort. No confounding factors or ED treatment strategies differed significantly between men with PsA and ED and comparators with ED. Conclusion. Men with PsA may have an increased risk of ED, which was detected but likely underpowered in this study. Whether this difference is secondary to higher prevalence of traditional risk factors of ED in men with PsA compared to the general population will require further study.",
keywords = "Erectile dysfunction, Key Indexing Terms: epidemiology, Psoriatic arthritis, Sexual dysfunction, Sexual health",
author = "Wilton, {Katelynn M.} and Achenbach, {Sara J.} and Paras Karmacharya and Ernste, {Floranne C.} and Matteson, {Eric L.} and Crowson, {Cynthia S.}",
note = "Funding Information: KMW was supported by the National Institutes of General Medical Sciences (grant T32-GM-65841) and is supported by the Mayo Clinic College of Medicine{\textquoteright}s Medical Scientist Training Program. Research reported in this publication was supported by the National Institute of Aging of the National Institutes of Health (NIH) under award number R01AG034676 and grant number UL1TR002377 from the National Center for Advancing Translational Sciences (NCATS), one of the institutes of the NIH. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. 1K.M. Wilton, BS, Medical Scientist Training Program, Mayo Clinic College of Medicine and Science; 2S.J. Achenbach, MS, Division of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine and Science; 3P. Karmacharya, MBBS, F.C. Ernste, MD, Division of Rheumatology, Mayo Clinic College of Medicine and Science; 4E.L. Matteson, MD, MPH, Division of Rheumatology, and Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine and Science; 5C.S. Crowson, PhD, Division of Biomedical Statistics and Informatics, and Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA. The authors declare no conflicts of interest. Address correspondence to Dr. C.S. Crowson, Mayo Clinic, 200 1st St. SW, Rochester, MN 55905, USA. Email: Crowson@mayo.edu. Full Release Article. For details see Reprints and Permissions at jrheum.org. Accepted for publication October 2, 2020. Publisher Copyright: {\textcopyright} 2021 Journal of Rheumatology. All rights reserved.",
year = "2021",
month = apr,
day = "1",
doi = "10.3899/JRHEUM.200903",
language = "English (US)",
volume = "48",
pages = "527--532",
journal = "Journal of Rheumatology",
issn = "0315-162X",
publisher = "Journal of Rheumatology",
number = "4",
}