Erdheim-Chester disease

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Imaging description Erdheim-Chester disease is a very rare interstitial lung disease characterized by infiltration of non-Langerhans cell histiocytes or macrophages forming granulomatous lesions with fibrosis. The bones are the primary site of involvement (osteosclerotic lesions) (Figures 17.1 and 17.2), but pulmonary involvement can occur. The infiltration occurs most prominently along the lymphatics, and therefore affects the interlobular septa, bronchovascular bundles, and visceral pleura. On high-resolution CT chest, the major findings are smooth thickening of the fissures and interlobular septa, ground-glass opacities, and centrilobular nodules, which are slightly more prominent in the mid and upper lungs (Figures 17.1–17.3) [1–3]. Pleural effusions are present in roughly 50% of cases (Figure 17.1). Other common findings include pericardial thickening or effusion and extrathoracic soft tissue masses. The extrathoracic soft tissue is often seen surrounding the kidneys and in the retroperitoneum (Figures 17.2 and 17.3) [2].

Original languageEnglish (US)
Title of host publicationPearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses
PublisherCambridge University Press
Pages44-47
Number of pages4
ISBN (Print)9780511977701, 9780521119078
DOIs
StatePublished - Jan 1 2011

Fingerprint

Erdheim-Chester Disease
Lung
Histiocytes
Pleura
Interstitial Lung Diseases
Pleural Effusion
Glass
Fibrosis
Thorax
Macrophages
Kidney
Bone and Bones

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Levin, D., & Sykes, A-M. G. (2011). Erdheim-Chester disease. In Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses (pp. 44-47). Cambridge University Press. https://doi.org/10.1017/CBO9780511977701.018

Erdheim-Chester disease. / Levin, David; Sykes, Anne-Marie Gisele.

Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses. Cambridge University Press, 2011. p. 44-47.

Research output: Chapter in Book/Report/Conference proceedingChapter

Levin, D & Sykes, A-MG 2011, Erdheim-Chester disease. in Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses. Cambridge University Press, pp. 44-47. https://doi.org/10.1017/CBO9780511977701.018
Levin D, Sykes A-MG. Erdheim-Chester disease. In Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses. Cambridge University Press. 2011. p. 44-47 https://doi.org/10.1017/CBO9780511977701.018
Levin, David ; Sykes, Anne-Marie Gisele. / Erdheim-Chester disease. Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses. Cambridge University Press, 2011. pp. 44-47
@inbook{9b0a65f7b5f343caa1c098f721bea305,
title = "Erdheim-Chester disease",
abstract = "Imaging description Erdheim-Chester disease is a very rare interstitial lung disease characterized by infiltration of non-Langerhans cell histiocytes or macrophages forming granulomatous lesions with fibrosis. The bones are the primary site of involvement (osteosclerotic lesions) (Figures 17.1 and 17.2), but pulmonary involvement can occur. The infiltration occurs most prominently along the lymphatics, and therefore affects the interlobular septa, bronchovascular bundles, and visceral pleura. On high-resolution CT chest, the major findings are smooth thickening of the fissures and interlobular septa, ground-glass opacities, and centrilobular nodules, which are slightly more prominent in the mid and upper lungs (Figures 17.1–17.3) [1–3]. Pleural effusions are present in roughly 50{\%} of cases (Figure 17.1). Other common findings include pericardial thickening or effusion and extrathoracic soft tissue masses. The extrathoracic soft tissue is often seen surrounding the kidneys and in the retroperitoneum (Figures 17.2 and 17.3) [2].",
author = "David Levin and Sykes, {Anne-Marie Gisele}",
year = "2011",
month = "1",
day = "1",
doi = "10.1017/CBO9780511977701.018",
language = "English (US)",
isbn = "9780511977701",
pages = "44--47",
booktitle = "Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses",
publisher = "Cambridge University Press",

}

TY - CHAP

T1 - Erdheim-Chester disease

AU - Levin, David

AU - Sykes, Anne-Marie Gisele

PY - 2011/1/1

Y1 - 2011/1/1

N2 - Imaging description Erdheim-Chester disease is a very rare interstitial lung disease characterized by infiltration of non-Langerhans cell histiocytes or macrophages forming granulomatous lesions with fibrosis. The bones are the primary site of involvement (osteosclerotic lesions) (Figures 17.1 and 17.2), but pulmonary involvement can occur. The infiltration occurs most prominently along the lymphatics, and therefore affects the interlobular septa, bronchovascular bundles, and visceral pleura. On high-resolution CT chest, the major findings are smooth thickening of the fissures and interlobular septa, ground-glass opacities, and centrilobular nodules, which are slightly more prominent in the mid and upper lungs (Figures 17.1–17.3) [1–3]. Pleural effusions are present in roughly 50% of cases (Figure 17.1). Other common findings include pericardial thickening or effusion and extrathoracic soft tissue masses. The extrathoracic soft tissue is often seen surrounding the kidneys and in the retroperitoneum (Figures 17.2 and 17.3) [2].

AB - Imaging description Erdheim-Chester disease is a very rare interstitial lung disease characterized by infiltration of non-Langerhans cell histiocytes or macrophages forming granulomatous lesions with fibrosis. The bones are the primary site of involvement (osteosclerotic lesions) (Figures 17.1 and 17.2), but pulmonary involvement can occur. The infiltration occurs most prominently along the lymphatics, and therefore affects the interlobular septa, bronchovascular bundles, and visceral pleura. On high-resolution CT chest, the major findings are smooth thickening of the fissures and interlobular septa, ground-glass opacities, and centrilobular nodules, which are slightly more prominent in the mid and upper lungs (Figures 17.1–17.3) [1–3]. Pleural effusions are present in roughly 50% of cases (Figure 17.1). Other common findings include pericardial thickening or effusion and extrathoracic soft tissue masses. The extrathoracic soft tissue is often seen surrounding the kidneys and in the retroperitoneum (Figures 17.2 and 17.3) [2].

UR - http://www.scopus.com/inward/record.url?scp=84923546742&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84923546742&partnerID=8YFLogxK

U2 - 10.1017/CBO9780511977701.018

DO - 10.1017/CBO9780511977701.018

M3 - Chapter

AN - SCOPUS:84923546742

SN - 9780511977701

SN - 9780521119078

SP - 44

EP - 47

BT - Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses

PB - Cambridge University Press

ER -