Epstein-Barr virus-associated nephrotic syndrome

Deana Mikhalkova; Sahil Khanna; Rakhee Vaidya; Sanjeev Sethi; Marie C. Hogan

doi:10.1093/ndtplus/sfr119

Epstein-Barr virus-associated nephrotic syndrome

Deana Mikhalkova, Sahil Khanna, Rakhee Vaidya, Sanjeev Sethi, Marie C. Hogan

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Acute infection with Epstein-Barr virus (EBV) causes fever, fatigue and pharyngitis. Renal involvement in systemic EBV infections typically manifests as acute tubular necrosis or tubulointerstitial nephritis. Rarely, EBV infection causes nephrotic syndrome due to minimal change disease. A 22-year-old male with infectious mononucleosis (IM) presented with nephrotic syndrome. Renal biopsy showed minimal change disease with diffuse foot process effacement of the podocytes. Treatment with methylprednisone led to rapid and complete clinical remission. Minimal change nephropathy is a very rare manifestation of EBV infection and should be considered in patients with IM and proteinuria.

Original language	English (US)
Pages (from-to)	50-52
Number of pages	3
Journal	Clinical Kidney Journal
Volume	5
Issue number	1
DOIs	https://doi.org/10.1093/ndtplus/sfr119
State	Published - Feb 1 2012

Keywords

infectious mononucleosis
minimal change disease
nephrotic syndrome

ASJC Scopus subject areas

Nephrology
Transplantation

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10.1093/ndtplus/sfr119

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abstract = "Acute infection with Epstein-Barr virus (EBV) causes fever, fatigue and pharyngitis. Renal involvement in systemic EBV infections typically manifests as acute tubular necrosis or tubulointerstitial nephritis. Rarely, EBV infection causes nephrotic syndrome due to minimal change disease. A 22-year-old male with infectious mononucleosis (IM) presented with nephrotic syndrome. Renal biopsy showed minimal change disease with diffuse foot process effacement of the podocytes. Treatment with methylprednisone led to rapid and complete clinical remission. Minimal change nephropathy is a very rare manifestation of EBV infection and should be considered in patients with IM and proteinuria.",

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AU - Mikhalkova, Deana

AU - Khanna, Sahil

AU - Vaidya, Rakhee

AU - Sethi, Sanjeev

AU - Hogan, Marie C.

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N2 - Acute infection with Epstein-Barr virus (EBV) causes fever, fatigue and pharyngitis. Renal involvement in systemic EBV infections typically manifests as acute tubular necrosis or tubulointerstitial nephritis. Rarely, EBV infection causes nephrotic syndrome due to minimal change disease. A 22-year-old male with infectious mononucleosis (IM) presented with nephrotic syndrome. Renal biopsy showed minimal change disease with diffuse foot process effacement of the podocytes. Treatment with methylprednisone led to rapid and complete clinical remission. Minimal change nephropathy is a very rare manifestation of EBV infection and should be considered in patients with IM and proteinuria.

AB - Acute infection with Epstein-Barr virus (EBV) causes fever, fatigue and pharyngitis. Renal involvement in systemic EBV infections typically manifests as acute tubular necrosis or tubulointerstitial nephritis. Rarely, EBV infection causes nephrotic syndrome due to minimal change disease. A 22-year-old male with infectious mononucleosis (IM) presented with nephrotic syndrome. Renal biopsy showed minimal change disease with diffuse foot process effacement of the podocytes. Treatment with methylprednisone led to rapid and complete clinical remission. Minimal change nephropathy is a very rare manifestation of EBV infection and should be considered in patients with IM and proteinuria.

KW - infectious mononucleosis

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Epstein-Barr virus-associated nephrotic syndrome

Abstract

Keywords

ASJC Scopus subject areas

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