Abstract
This paper presents a study on non-invasive detection of two common epithelial cancers (skin and esophagus) based on oblique incidence diffuse reflectance spectroscopy (OIDRS). An OIDRS measurement system, which combines fiber optics and MEMS technologies, was developed. In our pilot studies, a total number of 137 cases have been measured in-vivo for skin cancer detection and a total number of 20 biopsy samples have been measured ex-vivo for esophageal cancer detection. To automatically differentiate the cancerous cases from benign ones, a statistical software classification program was also developed. An overall classification accuracy of 90% and 100% has been achieved for skin and esophageal cancer classification, respectively.
Original language | English (US) |
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Article number | 71690A |
Journal | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
Volume | 7169 |
DOIs | |
State | Published - 2009 |
Event | Advanced Biomedical and Clinical Diagnostic Systems VII - San Jose, CA, United States Duration: Jan 25 2009 → Jan 26 2009 |
Keywords
- Cancer detection
- MEMS
- Oblique incidence
- Spectroscopy
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging
- Biomaterials