Abstract
International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled ‘Basic and Translational Facets of the Epigenetics of GI Diseases’. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI) diseases. Highlights of the meeting included recent advances on the involvement of different epigenetic mechanisms in malignant and nonmalignant GI disorders and the epigenetic heterogeneity exhibited in these diseases. The translational value of epigenetic drugs, as well as the current and future use of epigenetic changes (i.e., DNA methylation patterns) as biomarkers for early detection tools or disease stratification were also important topics of discussion.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 449-457 |
| Number of pages | 9 |
| Journal | Epigenetics |
| Volume | 13 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 3 2018 |
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Keywords
- biomarkers
- chromatin
- DNA methylation
- epigenetics
- Gastrointestinal diseases
- miRNA
- therapeutics
ASJC Scopus subject areas
- Molecular Biology
- Cancer Research
Cite this
Epigenetics of gastrointestinal diseases : notes from a workshop. / Marks, David L.; Olson, Rachel L.; Urrutia, Raul; Billadeau, Daniel D; Roy, Nilotpal; Calin, George A.; Fabbri, Muller; Koutsioumpa, Marina; Iliopoulos, Dimitrios; Ordog, Tamas; Huebert, Robert C; Sarmento, Olga; Bamidele, Adebowale O.; Faubion, William Alvis; Lomberk, Gwen L.; Siveke, Jens; Ahuja, Nita; Iovanna, Juan; Hlady, Ryan A.; Robertson, Keith D; Kisiel, John B; Pin, Christopher L.; Fernandez-Zapico, Martin E.
In: Epigenetics, Vol. 13, No. 4, 03.04.2018, p. 449-457.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Epigenetics of gastrointestinal diseases
T2 - notes from a workshop
AU - Marks, David L.
AU - Olson, Rachel L.
AU - Urrutia, Raul
AU - Billadeau, Daniel D
AU - Roy, Nilotpal
AU - Calin, George A.
AU - Fabbri, Muller
AU - Koutsioumpa, Marina
AU - Iliopoulos, Dimitrios
AU - Ordog, Tamas
AU - Huebert, Robert C
AU - Sarmento, Olga
AU - Bamidele, Adebowale O.
AU - Faubion, William Alvis
AU - Lomberk, Gwen L.
AU - Siveke, Jens
AU - Ahuja, Nita
AU - Iovanna, Juan
AU - Hlady, Ryan A.
AU - Robertson, Keith D
AU - Kisiel, John B
AU - Pin, Christopher L.
AU - Fernandez-Zapico, Martin E
PY - 2018/4/3
Y1 - 2018/4/3
N2 - International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled ‘Basic and Translational Facets of the Epigenetics of GI Diseases’. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI) diseases. Highlights of the meeting included recent advances on the involvement of different epigenetic mechanisms in malignant and nonmalignant GI disorders and the epigenetic heterogeneity exhibited in these diseases. The translational value of epigenetic drugs, as well as the current and future use of epigenetic changes (i.e., DNA methylation patterns) as biomarkers for early detection tools or disease stratification were also important topics of discussion.
AB - International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled ‘Basic and Translational Facets of the Epigenetics of GI Diseases’. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI) diseases. Highlights of the meeting included recent advances on the involvement of different epigenetic mechanisms in malignant and nonmalignant GI disorders and the epigenetic heterogeneity exhibited in these diseases. The translational value of epigenetic drugs, as well as the current and future use of epigenetic changes (i.e., DNA methylation patterns) as biomarkers for early detection tools or disease stratification were also important topics of discussion.
KW - biomarkers
KW - chromatin
KW - DNA methylation
KW - epigenetics
KW - Gastrointestinal diseases
KW - miRNA
KW - therapeutics
UR - http://www.scopus.com/inward/record.url?scp=85052053592&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85052053592&partnerID=8YFLogxK
U2 - 10.1080/15592294.2018.1464351
DO - 10.1080/15592294.2018.1464351
M3 - Article
C2 - 30056798
AN - SCOPUS:85052053592
VL - 13
SP - 449
EP - 457
JO - Epigenetics
JF - Epigenetics
SN - 1559-2294
IS - 4
ER -