Epigenetics of gastrointestinal diseases: notes from a workshop

David L. Marks, Rachel L. Olson, Raul Urrutia, Daniel D Billadeau, Nilotpal Roy, George A. Calin, Muller Fabbri, Marina Koutsioumpa, Dimitrios Iliopoulos, Tamas Ordog, Robert C Huebert, Olga Sarmento, Adebowale O. Bamidele, William Alvis Faubion, Gwen L. Lomberk, Jens Siveke, Nita Ahuja, Juan Iovanna, Ryan A. Hlady, Keith D RobertsonJohn B Kisiel, Christopher L. Pin, Martin E Fernandez-Zapico

Research output: Contribution to journalArticle

Abstract

International experts gathered at the Mayo Clinic (Rochester MN, USA) on February 27th-28th, 2017 for a meeting entitled ‘Basic and Translational Facets of the Epigenetics of GI Diseases’. This workshop summarized recent advances on the role of epigenetics in the pathobiology of gastrointestinal (GI) diseases. Highlights of the meeting included recent advances on the involvement of different epigenetic mechanisms in malignant and nonmalignant GI disorders and the epigenetic heterogeneity exhibited in these diseases. The translational value of epigenetic drugs, as well as the current and future use of epigenetic changes (i.e., DNA methylation patterns) as biomarkers for early detection tools or disease stratification were also important topics of discussion.

Original languageEnglish (US)
Pages (from-to)449-457
Number of pages9
JournalEpigenetics
Volume13
Issue number4
DOIs
StatePublished - Apr 3 2018

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Gastrointestinal Diseases
Epigenomics
Education
DNA Methylation
Biomarkers
Pharmaceutical Preparations

Keywords

  • biomarkers
  • chromatin
  • DNA methylation
  • epigenetics
  • Gastrointestinal diseases
  • miRNA
  • therapeutics

ASJC Scopus subject areas

  • Molecular Biology
  • Cancer Research

Cite this

Epigenetics of gastrointestinal diseases : notes from a workshop. / Marks, David L.; Olson, Rachel L.; Urrutia, Raul; Billadeau, Daniel D; Roy, Nilotpal; Calin, George A.; Fabbri, Muller; Koutsioumpa, Marina; Iliopoulos, Dimitrios; Ordog, Tamas; Huebert, Robert C; Sarmento, Olga; Bamidele, Adebowale O.; Faubion, William Alvis; Lomberk, Gwen L.; Siveke, Jens; Ahuja, Nita; Iovanna, Juan; Hlady, Ryan A.; Robertson, Keith D; Kisiel, John B; Pin, Christopher L.; Fernandez-Zapico, Martin E.

In: Epigenetics, Vol. 13, No. 4, 03.04.2018, p. 449-457.

Research output: Contribution to journalArticle

Marks, DL, Olson, RL, Urrutia, R, Billadeau, DD, Roy, N, Calin, GA, Fabbri, M, Koutsioumpa, M, Iliopoulos, D, Ordog, T, Huebert, RC, Sarmento, O, Bamidele, AO, Faubion, WA, Lomberk, GL, Siveke, J, Ahuja, N, Iovanna, J, Hlady, RA, Robertson, KD, Kisiel, JB, Pin, CL & Fernandez-Zapico, ME 2018, 'Epigenetics of gastrointestinal diseases: notes from a workshop', Epigenetics, vol. 13, no. 4, pp. 449-457. https://doi.org/10.1080/15592294.2018.1464351
Marks, David L. ; Olson, Rachel L. ; Urrutia, Raul ; Billadeau, Daniel D ; Roy, Nilotpal ; Calin, George A. ; Fabbri, Muller ; Koutsioumpa, Marina ; Iliopoulos, Dimitrios ; Ordog, Tamas ; Huebert, Robert C ; Sarmento, Olga ; Bamidele, Adebowale O. ; Faubion, William Alvis ; Lomberk, Gwen L. ; Siveke, Jens ; Ahuja, Nita ; Iovanna, Juan ; Hlady, Ryan A. ; Robertson, Keith D ; Kisiel, John B ; Pin, Christopher L. ; Fernandez-Zapico, Martin E. / Epigenetics of gastrointestinal diseases : notes from a workshop. In: Epigenetics. 2018 ; Vol. 13, No. 4. pp. 449-457.
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