Epigenetics

Gwen Lomberk

Research output: Contribution to journalShort survey

1 Citation (Scopus)

Abstract

'Epigenetics', the term that is used for the study of heritable changes in gene function that occur without a change in the DNA sequence, has become a significant area of research. As a consequence of this emerging field, our concepts founded upon genetics alone have been blurred and the way researchers think about heredity has changed. Epigenetic mechanisms such as DNA methylation, histone modifications ('histone code'), chromatin modifiers, RNA interference as well as their effects in gene activation and inactivation are increasingly understood to be more than 'sideline players' in phenotype transmission and development, which consequently impacts significantly on our study of disease states such as cancer.

Original languageEnglish (US)
Pages (from-to)396-397
Number of pages2
JournalPancreatology
Volume7
Issue number5-6
DOIs
StatePublished - Oct 2007

Fingerprint

Histone Code
Epigenomics
Heredity
Gene Silencing
DNA Methylation
RNA Interference
Transcriptional Activation
Chromatin
Research Personnel
Phenotype
Research
Genes
Neoplasms

ASJC Scopus subject areas

  • Endocrinology
  • Gastroenterology

Cite this

Lomberk, G. (2007). Epigenetics. Pancreatology, 7(5-6), 396-397. https://doi.org/10.1159/000108954

Epigenetics. / Lomberk, Gwen.

In: Pancreatology, Vol. 7, No. 5-6, 10.2007, p. 396-397.

Research output: Contribution to journalShort survey

Lomberk, G 2007, 'Epigenetics', Pancreatology, vol. 7, no. 5-6, pp. 396-397. https://doi.org/10.1159/000108954
Lomberk G. Epigenetics. Pancreatology. 2007 Oct;7(5-6):396-397. https://doi.org/10.1159/000108954
Lomberk, Gwen. / Epigenetics. In: Pancreatology. 2007 ; Vol. 7, No. 5-6. pp. 396-397.
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