Epidermoids of the cerebellopontine angle: a 20-year experience

Background: There is considerable debate within the current literature whether total or subtotal removal of CPA epidermoids yields better long-term outcomes. The aim of this study was to review our experience with cerebellopontine-angle epidermoid tumors, as well as the current literature, focusing on the correlation between long-term outcome and the extent of surgical removal. Methods: We performed a retrospective review of 24 patients with epidermoid tumors of the CPA surgically treated at our institution between 1985 and 2005. Results: The mean duration from onset of symptoms to surgery was 3.1 years. Cranial nerve dysfunction was noted in 83% of patients preoperatively. Total removal was achieved in 13 patients, near total removal in 6 patients, and subtotal removal in 5 patients. Patients who underwent total removal had a median MRS score of 0, whereas those who underwent near/subtotal removal had a median MRS score of 1. The rate of recurrence was 23% in tumors considered totally removed and 27% in those near/subtotally removed. Of the 6 patients with recurrences, 5 underwent a second operation. The mean duration of follow-up was 4.2 years. Conclusions: Total removal of CPA epidermoids does not result in significantly increased morbidity and mortality and should be the goal of surgical treatment. However, near/subtotal resection of lesions that extend far beyond the CPA or are densely adherent to neurovascular structures is justified, as there is no significant difference in the rate of recurrence.