Epidermal growth factor stimulates production of progesterone in cultured human choriocarcinoma cells

Rebecca S. Bahn, K. V. Speeg, Mario Ascoli, David Rabin

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Epidermal growth factor (EGF) stimulates the production of progesterone by JEG-3, a clonal strain of human choriocarcinoma cells. Stimulation occurs in a time and dose-dependent manner. In addition, EGF increases [14C]-acetate incorporation into [14C]-cholesterol in JEG-3 cells, and this may constitute its mechanism of action in enhancing progesterone synthesis.

Original languageEnglish (US)
Pages (from-to)2121-2123
Number of pages3
JournalEndocrinology
Volume107
Issue number6
DOIs
StatePublished - Jan 1 1980
Externally publishedYes

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Choriocarcinoma
Epidermal Growth Factor
Progesterone
Acetates
Cholesterol

ASJC Scopus subject areas

  • Endocrinology

Cite this

Epidermal growth factor stimulates production of progesterone in cultured human choriocarcinoma cells. / Bahn, Rebecca S.; Speeg, K. V.; Ascoli, Mario; Rabin, David.

In: Endocrinology, Vol. 107, No. 6, 01.01.1980, p. 2121-2123.

Research output: Contribution to journalArticle

Bahn, Rebecca S. ; Speeg, K. V. ; Ascoli, Mario ; Rabin, David. / Epidermal growth factor stimulates production of progesterone in cultured human choriocarcinoma cells. In: Endocrinology. 1980 ; Vol. 107, No. 6. pp. 2121-2123.
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