Epidermal growth factor stimulates production of progesterone in cultured human choriocarcinoma cells

Rebecca S. Bahn, K. V. Speeg, Mario Ascoli, David Rabin

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Epidermal growth factor (EGF) stimulates the production of progesterone by JEG-3, a clonal strain of human choriocarcinoma cells. Stimulation occurs in a time and dose-dependent manner. In addition, EGF increases [14C]-acetate incorporation into [14C]-cholesterol in JEG-3 cells, and this may constitute its mechanism of action in enhancing progesterone synthesis.

Original languageEnglish (US)
Pages (from-to)2121-2123
Number of pages3
JournalEndocrinology
Volume107
Issue number6
DOIs
StatePublished - Dec 1980

ASJC Scopus subject areas

  • Endocrinology

Fingerprint Dive into the research topics of 'Epidermal growth factor stimulates production of progesterone in cultured human choriocarcinoma cells'. Together they form a unique fingerprint.

  • Cite this