Epidemiology of spinal osteoporosis

L. Joseph Melton

Research output: Contribution to journalArticle

303 Citations (Scopus)

Abstract

Approximately 30% of postmenopausal white women in the United States have osteoporosis and 16% have osteoporosis of the lumbar spine in particular. Bone density of the spine is positively associated with greater height and weight, older age at menopause, a history of arthritis, more physical activity, moderate use of alcoholic beverages, diuretic treatment, and current estrogen replacement therapy, whereas later age at menarche and a maternal history of fracture are associated with lower levels of density. Low bone density leads to an increased risk of osteoporotic fractures. Fracture risk also increase with age. Vertebral fractures affect approximately 25% of postmenopausal woman, although the exact figure depends on the definition used. Recent data show that vertebral fracture rates are as great in men as in women but, because women live longer, the lifetime risk of a vertebral fracture from age 50 onward is 16% in white women and only 5% in white men. Fracture rates are less in most nonwhite populations, but vertebral fractures are as common in Asian women as in those of European heritage. Other risk factors for vertebral fractures are less clear but include hypogonadism and secondary osteoporosis, obesity is protective of fractures as it is of bone loss. Compared with hip fractures, vertebral fractures are less disabling and less expensive, costing approximately $746 million in the United States in 1995. However, they have a substantial negative impact on the patient's function and quality of life. The adverse effects of osteoporotic fractures are likely to increase in the future with the growing number of elderly people.

Original languageEnglish (US)
JournalSpine
Volume22
Issue number24 SUPPL.
StatePublished - Dec 15 1997

Fingerprint

Osteoporosis
Epidemiology
Osteoporotic Fractures
Bone Density
Spine
Alcoholic Beverages
Menarche
Estrogen Replacement Therapy
Hypogonadism
Hip Fractures
Menopause
Diuretics
Arthritis
Obesity
Mothers
Quality of Life
Exercise
Weights and Measures
Bone and Bones
Population

Keywords

  • Cost
  • Epidemiology
  • Osteoporosis
  • Outcomes
  • Risk factors
  • Vertebral fracture

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

Melton, L. J. (1997). Epidemiology of spinal osteoporosis. Spine, 22(24 SUPPL.).

Epidemiology of spinal osteoporosis. / Melton, L. Joseph.

In: Spine, Vol. 22, No. 24 SUPPL., 15.12.1997.

Research output: Contribution to journalArticle

Melton, LJ 1997, 'Epidemiology of spinal osteoporosis', Spine, vol. 22, no. 24 SUPPL..
Melton LJ. Epidemiology of spinal osteoporosis. Spine. 1997 Dec 15;22(24 SUPPL.).
Melton, L. Joseph. / Epidemiology of spinal osteoporosis. In: Spine. 1997 ; Vol. 22, No. 24 SUPPL.
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