Epidemiology of Pancreatitis

Dhiraj Yadav, Santhi Swaroop Vege, Suresh T. Chari

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Abstract

The annual incidence of acute pancreatitis (AP) is ∼20-40/100,000 population. The incidence has increased over the past 2-3 decades, mainly from a rising incidence of gallstone AP and increased testing for pancreatitis. The case-fatality has decreased. Severity of AP is related to demographic factors (age, obesity), local complications (pancreatic necrosis, fluid collections), and organ failure. The annual incidence of chronic pancreatitis (CP) is ∼4-9/100,000, and its prevalence ∼40/100,000 population. CP incidence is increasing but less than AP. Alcohol is the commonest single etiology and smoking is now an established risk factor. Several genetic factors that increase pancreatitis risk have been identified. Natural history of CP depends on the age at presentation and etiology. Quality of life in CP patients is significantly decreased, and their mortality is 3-4 times greater than general population. AP progresses to CP in a subset of patients, more commonly in the setting of alcohol consumption and smoking. This edition first published 2014

Original languageEnglish (US)
Title of host publicationGI Epidemiology
Subtitle of host publicationDiseases and Clinical Methodology: Second Edition
PublisherWiley-Blackwell
Pages306-312
Number of pages7
ISBN (Electronic)9781118727072
ISBN (Print)9780470672570
DOIs
StatePublished - Jan 13 2014

Keywords

  • Acute
  • Alcohol
  • Chronic
  • Epidemiology
  • Etiology
  • Incidence
  • Mortality
  • Pancreatitis
  • Prevalence
  • Smoking

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Yadav, D., Vege, S. S., & Chari, S. T. (2014). Epidemiology of Pancreatitis. In GI Epidemiology: Diseases and Clinical Methodology: Second Edition (pp. 306-312). Wiley-Blackwell. https://doi.org/10.1002/9781118727072.ch27