Epidemiology of Inflammatory Bowel Disease

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Crohn's disease and ulcerative colitis are the two major subtypes of idiopathic inflammatory bowel disease. The incidence of both diseases continues to rise in both the developed and developing world. The best established environmental factors are cigarette smoking (protective for ulcerative colitis, risk factor for Crohn's) and appendectomy (protective colitis). Antibiotic use, especially early in life, may be a risk factor for both conditions. Up to 30% of ulcerative colitis patients and 60-80% of Crohn's disease patients require surgery. Colorectal cancer risk is increased in ulcerative colitis and Crohn's disease with colonic involvement, while Crohn's disease patients with small bowel involvement are at increased risk for small bowel cancer. Mortality rates in Crohn's disease are increased, while mortality data in ulcerative colitis are conflicting. This edition first published 2014

Original languageEnglish (US)
Title of host publicationGI Epidemiology: Diseases and Clinical Methodology: Second Edition
PublisherWiley Blackwell
Pages273-284
Number of pages12
ISBN (Electronic)9781118727072
ISBN (Print)9780470672570
DOIs
StatePublished - Jan 13 2014

Keywords

  • Appendectomy
  • Cancer
  • Cigarette smoking
  • Crohn's disease
  • Epidemiology
  • Inflammatory bowel diseases
  • Mortality
  • Natural history
  • Risk factors
  • Surgery
  • Ulcerative colitis

ASJC Scopus subject areas

  • Medicine(all)

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