TY - JOUR
T1 - Epidemiology of Celiac Sprue
T2 - A Community‐based Study
AU - Talley, Nicholas J.
AU - Valdovinos, Miguel
AU - Petterson, Tanya M.
AU - Carpenter, Herschel A.
AU - Melton, L. Joseph
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1994/6
Y1 - 1994/6
N2 - Objective: To address the frequency and outcome of celiac disease in a United States community. Methods: We identified all Olmsted County, Minnesota, residents diagnosed with this condition during the period, 1960 through 1990, using the resources of the Rochester Epidemiology Project. Twenty‐eight incident cases (19 women, nine men) were identified. Results: The overall age‐ and gender‐adjusted incidence of celiac disease in the community was 1.2 per 100,000 person‐yr (95% CI 0.7,1.6). There were no significant changes in incidence over time, although rates did increase; the incidence was similar in men and women and rose with age in both genders (p < 0.05). Survival in this inception cohort was 100% at 6 months and 96% at 5 yr, which was not significantly different from expected. The estimated prevalence on January 1, 1991, was 21.8 per 100,000. Conclusion: This study provides the first epi‐demiologic data on celiac disease in the United States.
AB - Objective: To address the frequency and outcome of celiac disease in a United States community. Methods: We identified all Olmsted County, Minnesota, residents diagnosed with this condition during the period, 1960 through 1990, using the resources of the Rochester Epidemiology Project. Twenty‐eight incident cases (19 women, nine men) were identified. Results: The overall age‐ and gender‐adjusted incidence of celiac disease in the community was 1.2 per 100,000 person‐yr (95% CI 0.7,1.6). There were no significant changes in incidence over time, although rates did increase; the incidence was similar in men and women and rose with age in both genders (p < 0.05). Survival in this inception cohort was 100% at 6 months and 96% at 5 yr, which was not significantly different from expected. The estimated prevalence on January 1, 1991, was 21.8 per 100,000. Conclusion: This study provides the first epi‐demiologic data on celiac disease in the United States.
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U2 - 10.1111/j.1572-0241.1994.tb03167.x
DO - 10.1111/j.1572-0241.1994.tb03167.x
M3 - Article
C2 - 7864924
AN - SCOPUS:0028263499
SN - 0002-9270
VL - 89
SP - 843
EP - 846
JO - The American Journal of Gastroenterology
JF - The American Journal of Gastroenterology
IS - 6
ER -