Epidemiology of amyotrophic lateral sclerosis in Minnesota: A year-long population based study

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

This is the largest population based study of ALS in the U.S., encompassing the population of Minnesota (> 5.4 million people) from July 2013 to July 2014. Data on gender, age at diagnosis, and residential county were collected for all Minnesota residents who registered with the Minnesota/North Dakota/South Dakota chapter of the ALS Association from July 2013 to July 2014. Incidence rates were calculated as the number of new cases of ALS per 100,000 people per year. The standardized incidence rates for the 2013 U.S. population and the 2013 European standard population were also reported. Results showed that the crude incidence rate of ALS was 2.2 cases per 100,000 person-years. Incidence increased with age, peaking at 70-79 years (8.3 per 100,000) with mean age at diagnosis 64 years, and was greater in males (2.4 per 100,000) than in females (1.5 per 100,000). Standardized incidence rates for the 2013 U.S. and European standard population were 2.2 and 2.39 cases per 100,000 person-years, respectively. In conclusion, the overall incidence and age and gender patterns of ALS in Minnesota are comparable to those reported by European studies (1-5).

Original languageEnglish (US)
Pages (from-to)520-523
Number of pages4
JournalAmyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Volume16
Issue number7-8
DOIs
StatePublished - Nov 27 2015

Keywords

  • Epidemiology
  • risk
  • survival

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Fingerprint Dive into the research topics of 'Epidemiology of amyotrophic lateral sclerosis in Minnesota: A year-long population based study'. Together they form a unique fingerprint.

Cite this