Epidemiology, diagnosis and early patient management of esophagogastric hemorrhage

Sumit Kumar, Sumeet K. Asrani, Patrick Sequeira Kamath

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Acute variceal bleeding (AVB) is a potentially life-threatening complication of cirrhosis and portal hypertension. Combination therapy with vasoactive drugs and endoscopic variceal ligation is the first-line treatment in the management of AVB after adequate hemodynamic resuscitation. Short-term antibiotic prophylaxis, early resuscitation, early use of lactulose for prevention of hepatic encephalopathy, targeting of conservative goals for blood transfusion, and application of early transjugular intrahepatic portosystemic shunts in patients with AVB have further improved the prognosis of AVB. This article discusses the epidemiology, diagnosis, and nonendoscopic management of AVB.

Original languageEnglish (US)
Pages (from-to)765-782
Number of pages18
JournalGastroenterology Clinics of North America
Volume43
Issue number4
DOIs
StatePublished - Dec 1 2014

Fingerprint

Epidemiology
Hemorrhage
Resuscitation
Transjugular Intrahepatic Portasystemic Shunt
Lactulose
Antibiotic Prophylaxis
Hepatic Encephalopathy
Portal Hypertension
Blood Transfusion
Ligation
Fibrosis
Hemodynamics
Therapeutics
Pharmaceutical Preparations

Keywords

  • Acute variceal bleeding
  • Endoscopic variceal ligation
  • Esophageal varices
  • Gastric varices

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Epidemiology, diagnosis and early patient management of esophagogastric hemorrhage. / Kumar, Sumit; Asrani, Sumeet K.; Kamath, Patrick Sequeira.

In: Gastroenterology Clinics of North America, Vol. 43, No. 4, 01.12.2014, p. 765-782.

Research output: Contribution to journalArticle

@article{f1f96f6946ed408188cd34e4c8812ad3,
title = "Epidemiology, diagnosis and early patient management of esophagogastric hemorrhage",
abstract = "Acute variceal bleeding (AVB) is a potentially life-threatening complication of cirrhosis and portal hypertension. Combination therapy with vasoactive drugs and endoscopic variceal ligation is the first-line treatment in the management of AVB after adequate hemodynamic resuscitation. Short-term antibiotic prophylaxis, early resuscitation, early use of lactulose for prevention of hepatic encephalopathy, targeting of conservative goals for blood transfusion, and application of early transjugular intrahepatic portosystemic shunts in patients with AVB have further improved the prognosis of AVB. This article discusses the epidemiology, diagnosis, and nonendoscopic management of AVB.",
keywords = "Acute variceal bleeding, Endoscopic variceal ligation, Esophageal varices, Gastric varices",
author = "Sumit Kumar and Asrani, {Sumeet K.} and Kamath, {Patrick Sequeira}",
year = "2014",
month = "12",
day = "1",
doi = "10.1016/j.gtc.2014.08.007",
language = "English (US)",
volume = "43",
pages = "765--782",
journal = "Gastroenterology Clinics of North America",
issn = "0889-8553",
publisher = "W.B. Saunders Ltd",
number = "4",

}

TY - JOUR

T1 - Epidemiology, diagnosis and early patient management of esophagogastric hemorrhage

AU - Kumar, Sumit

AU - Asrani, Sumeet K.

AU - Kamath, Patrick Sequeira

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Acute variceal bleeding (AVB) is a potentially life-threatening complication of cirrhosis and portal hypertension. Combination therapy with vasoactive drugs and endoscopic variceal ligation is the first-line treatment in the management of AVB after adequate hemodynamic resuscitation. Short-term antibiotic prophylaxis, early resuscitation, early use of lactulose for prevention of hepatic encephalopathy, targeting of conservative goals for blood transfusion, and application of early transjugular intrahepatic portosystemic shunts in patients with AVB have further improved the prognosis of AVB. This article discusses the epidemiology, diagnosis, and nonendoscopic management of AVB.

AB - Acute variceal bleeding (AVB) is a potentially life-threatening complication of cirrhosis and portal hypertension. Combination therapy with vasoactive drugs and endoscopic variceal ligation is the first-line treatment in the management of AVB after adequate hemodynamic resuscitation. Short-term antibiotic prophylaxis, early resuscitation, early use of lactulose for prevention of hepatic encephalopathy, targeting of conservative goals for blood transfusion, and application of early transjugular intrahepatic portosystemic shunts in patients with AVB have further improved the prognosis of AVB. This article discusses the epidemiology, diagnosis, and nonendoscopic management of AVB.

KW - Acute variceal bleeding

KW - Endoscopic variceal ligation

KW - Esophageal varices

KW - Gastric varices

UR - http://www.scopus.com/inward/record.url?scp=84908226709&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908226709&partnerID=8YFLogxK

U2 - 10.1016/j.gtc.2014.08.007

DO - 10.1016/j.gtc.2014.08.007

M3 - Article

C2 - 25440924

AN - SCOPUS:84908226709

VL - 43

SP - 765

EP - 782

JO - Gastroenterology Clinics of North America

JF - Gastroenterology Clinics of North America

SN - 0889-8553

IS - 4

ER -