Abstract
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly named Churg-Strauss syndrome, is a rare systemic small- and medium-sized-vessel vasculitis, characterized by the presence of severe asthma as well as blood and tissue eosinophilia. Gastrointestinal (GI) symptoms, like diarrhea and abdominal pain, are common; however, there are few reports of histologic evidence of GI involvement. We report the case of a patient on treatment for EGPA who presented with recurrent small bowel obstruction and choledocholithiasis. Biopsies of the esophagus, small bowel and common bile duct showed diffuse eosinophilia, with clear EGPA in the GI tract. Improved awareness of GI EGPA may allow for timely management of this disorder.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 329-336 |
| Number of pages | 8 |
| Journal | Case Reports in Gastroenterology |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| State | Published - Apr 12 2014 |
Fingerprint
Keywords
- Cholangitis
- Eosinophilic granulomatosis with polyangiitis
- Gastrointestinal tract
- Small bowel obstruction
ASJC Scopus subject areas
- Gastroenterology
Cite this
Eosinophilic granulomatosis with polyangiitis and diffuse gastrointestinal involvement. / Franco, Diana L.; Ruff, Kevin; Mertz, Lester; Lam-Himlin, Dora M.; Heigh, Russell.
In: Case Reports in Gastroenterology, Vol. 8, No. 3, 12.04.2014, p. 329-336.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Eosinophilic granulomatosis with polyangiitis and diffuse gastrointestinal involvement
AU - Franco, Diana L.
AU - Ruff, Kevin
AU - Mertz, Lester
AU - Lam-Himlin, Dora M.
AU - Heigh, Russell
PY - 2014/4/12
Y1 - 2014/4/12
N2 - Eosinophilic granulomatosis with polyangiitis (EGPA), formerly named Churg-Strauss syndrome, is a rare systemic small- and medium-sized-vessel vasculitis, characterized by the presence of severe asthma as well as blood and tissue eosinophilia. Gastrointestinal (GI) symptoms, like diarrhea and abdominal pain, are common; however, there are few reports of histologic evidence of GI involvement. We report the case of a patient on treatment for EGPA who presented with recurrent small bowel obstruction and choledocholithiasis. Biopsies of the esophagus, small bowel and common bile duct showed diffuse eosinophilia, with clear EGPA in the GI tract. Improved awareness of GI EGPA may allow for timely management of this disorder.
AB - Eosinophilic granulomatosis with polyangiitis (EGPA), formerly named Churg-Strauss syndrome, is a rare systemic small- and medium-sized-vessel vasculitis, characterized by the presence of severe asthma as well as blood and tissue eosinophilia. Gastrointestinal (GI) symptoms, like diarrhea and abdominal pain, are common; however, there are few reports of histologic evidence of GI involvement. We report the case of a patient on treatment for EGPA who presented with recurrent small bowel obstruction and choledocholithiasis. Biopsies of the esophagus, small bowel and common bile duct showed diffuse eosinophilia, with clear EGPA in the GI tract. Improved awareness of GI EGPA may allow for timely management of this disorder.
KW - Cholangitis
KW - Eosinophilic granulomatosis with polyangiitis
KW - Gastrointestinal tract
KW - Small bowel obstruction
UR - http://www.scopus.com/inward/record.url?scp=84927669021&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927669021&partnerID=8YFLogxK
U2 - 10.1159/000369129
DO - 10.1159/000369129
M3 - Article
AN - SCOPUS:84927669021
VL - 8
SP - 329
EP - 336
JO - Case Reports in Gastroenterology
JF - Case Reports in Gastroenterology
SN - 1662-0631
IS - 3
ER -