TY - JOUR
T1 - Eosinophilic Esophagitis in Adults
AU - Prasad, Ganapathy A.
AU - Talley, Nicholas J.
PY - 2008/6
Y1 - 2008/6
N2 - Eosinophilic esophagitis in adults is a disease characterized by eosinophilic infiltration of the esophageal mucosa and symptoms of long-standing solid food dysphagia and food impactions. First described in 1978, this syndrome is being recognized increasingly in the developed world, with multiple case series reported from the United States, Europe, and Australia during the past decade. Diagnosis requires the presence of greater than or equal to 15 eosinophils/high-power field on esophageal biopsies. Successful treatment in adults has been reported with the use of systemic and topical swallowed steroids. Endoscopic treatment has been associated with increased an risk for tears and perforations.
AB - Eosinophilic esophagitis in adults is a disease characterized by eosinophilic infiltration of the esophageal mucosa and symptoms of long-standing solid food dysphagia and food impactions. First described in 1978, this syndrome is being recognized increasingly in the developed world, with multiple case series reported from the United States, Europe, and Australia during the past decade. Diagnosis requires the presence of greater than or equal to 15 eosinophils/high-power field on esophageal biopsies. Successful treatment in adults has been reported with the use of systemic and topical swallowed steroids. Endoscopic treatment has been associated with increased an risk for tears and perforations.
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U2 - 10.1016/j.gtc.2008.03.002
DO - 10.1016/j.gtc.2008.03.002
M3 - Review article
C2 - 18499024
AN - SCOPUS:43549110703
SN - 0889-8553
VL - 37
SP - 349
EP - 368
JO - Gastroenterology Clinics of North America
JF - Gastroenterology Clinics of North America
IS - 2
ER -