Objective: The current study was undertaken to assess the frequency of excessive enteric protein loss and protein-losing enteropathy in the relatively early period after the Fontan operation. Design: Protein excretion was determined in 26 of 27 consecutive patients who underwent the Fontan procedure between January and June 1990 at the Mayo Clinic. Material and Methods: At two testing intervals during the first 4 months after the Fontan operation, α1-antitrypsin clearance and fecal α1-antitrypsin concentration studies were done. Results: All results were normal for the first postoperative test period (2 to 8 weeks). For the second study period, all 17 patients tested had normal α1-antitrypsin clearances. One of the 17 patients had an appreciably increased fecal α1-antitrypsin concentration and transient protein-losing enteropathy. Conclusion: Excessive enteric protein loss and protein-losing enteropathy are relatively uncommon during the first 4 months after the Fontan operation.
|Original language||English (US)|
|Number of pages||3|
|Journal||Mayo Clinic Proceedings|
|State||Published - 1994|
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