Endovascular repair of saccular ascending aortic aneurysm after orthotopic heart transplantation using an investigational Zenith Ascend stent-graft

Gustavo Oderich, Alberto Pochettino, Bernardo C. Mendes, Blayne Roeder, Juan Pulido, Peter Gloviczki

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: To report the use of an investigational stent-graft to treat an ascending aortic aneurysm in a patient with a heart transplant. Case Report: A 48-year-old man presented with a 3.5×1.5-cm saccular aneurysm in the mid anterior ascending aorta, abutting the sternum. The patient's history was notable for placement of a left ventricular assist device followed by orthotopic heart transplantation 2 years prior to treat end-stage familial dilated cardiomyopathy. Under compassionate use, a custom-designed ascending aortic stent-graft (Zenith Ascend) was successfully delivered via an 18-F system and deployed just distal to the origin of the left main coronary artery under pulmonary artery catheter - guided rapid ventricular pacing. The patient was discharged the next day, and 6-month follow-up was unremarkable. Imaging at 5 months showed an excluded aneurysm sac with no endoleak or migration. Conclusion: The ideal ascending aortic stentgraft should be low profile, conformable to the arch anatomy, with short tip delivery system and a stepwise deployment mechanism that allows precise placement relative to the ostia of the coronary arteries and the innominate artery. This case illustrates the advancement of endovascular techniques to the most challenging segment of the aorta to decrease morbidity and mortality in high-risk patients.

Original languageEnglish (US)
Pages (from-to)650-654
Number of pages5
JournalJournal of Endovascular Therapy
Volume22
Issue number4
DOIs
StatePublished - Jan 1 2015

Fingerprint

Aortic Aneurysm
Heart Transplantation
Stents
Transplants
Aneurysm
Aorta
Coronary Vessels
Compassionate Use Trials
Brachiocephalic Trunk
Endoleak
Endovascular Procedures
Sternum
Heart-Assist Devices
Pulmonary Artery
Anatomy
Catheters
Morbidity
Mortality

Keywords

  • Ascending aorta
  • Heart transplantation
  • Saccular aneurysm
  • Stent-graft
  • Thoracic endovascular aortic repair

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Endovascular repair of saccular ascending aortic aneurysm after orthotopic heart transplantation using an investigational Zenith Ascend stent-graft. / Oderich, Gustavo; Pochettino, Alberto; Mendes, Bernardo C.; Roeder, Blayne; Pulido, Juan; Gloviczki, Peter.

In: Journal of Endovascular Therapy, Vol. 22, No. 4, 01.01.2015, p. 650-654.

Research output: Contribution to journalArticle

Oderich, Gustavo ; Pochettino, Alberto ; Mendes, Bernardo C. ; Roeder, Blayne ; Pulido, Juan ; Gloviczki, Peter. / Endovascular repair of saccular ascending aortic aneurysm after orthotopic heart transplantation using an investigational Zenith Ascend stent-graft. In: Journal of Endovascular Therapy. 2015 ; Vol. 22, No. 4. pp. 650-654.
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