Endothelium-dependent responses and their potential relevance to the distribution of blood flow during hemorrhagic shock

Virginia M Miller, Paul M. Vanhoutte

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The endothelium releases vasoactive substances in response to several circulating hormones and to changes in shear stress of the flowing blood across the endothelial surface. Because the distribution of receptors mediating the release of endothelium-derived factors is not uniform along the vascular bed, the vascular endothelium has a potential role in regulating regional blood flow and maintaining peripheral resistance during the course and recovery from hemorrhagic shock.

Original languageEnglish (US)
Pages (from-to)165-171
Number of pages7
JournalResuscitation
Volume18
Issue number2-3
DOIs
StatePublished - 1989

Keywords

  • Acetylcholine
  • Adrenoceptors
  • Arginine vasopressin
  • Endothelin
  • Endothelium-derived contracting factor and relaxing factor
  • Nitric oxide
  • Renin

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nursing(all)

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