TY - JOUR
T1 - Endothelial function and cerebrovascular disease
T2 - Implications for diagnosis and treatment
AU - Elesber, Ahmad A.
AU - Bonetti, Piero O.
AU - Lerman, Amir
PY - 2006/6
Y1 - 2006/6
N2 - Cerebrovascular disease remains one of the most common causes of morbidity and mortality in the United States. There is strong evidence to implicate endothelial dysfunction in the initiation and progression of atherosclerosis and its complications. It is now well known that endothelial dysfunction represents a systemic syndrome involving multiple vascular beds, including the cerebral vasculature. Currently, no gold standard treatment for endothelial dysfunction exists. Nonetheless, several treatment strategies have been found to be helpful in improving endothelial function. A few of these strategies have been implicated in stroke risk reduction as well, adding another line of evidence to the relationship between endothelial function and cerebrovascular disease.
AB - Cerebrovascular disease remains one of the most common causes of morbidity and mortality in the United States. There is strong evidence to implicate endothelial dysfunction in the initiation and progression of atherosclerosis and its complications. It is now well known that endothelial dysfunction represents a systemic syndrome involving multiple vascular beds, including the cerebral vasculature. Currently, no gold standard treatment for endothelial dysfunction exists. Nonetheless, several treatment strategies have been found to be helpful in improving endothelial function. A few of these strategies have been implicated in stroke risk reduction as well, adding another line of evidence to the relationship between endothelial function and cerebrovascular disease.
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U2 - 10.1007/s11936-006-0014-x
DO - 10.1007/s11936-006-0014-x
M3 - Article
C2 - 16635440
AN - SCOPUS:33646787847
SN - 1092-8464
VL - 8
SP - 213
EP - 219
JO - Current Treatment Options in Cardiovascular Medicine
JF - Current Treatment Options in Cardiovascular Medicine
IS - 3
ER -