Endoscopic treatment of chronic radiation proctopathy

Christopher J. Gostout

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations

Abstract

Radiation proctopathy can be a disabling delayed outcome of radiation therapy directed at pelvic malignancies. Rectal outlet bleeding can be severe enough to result in anemia and transfusion dependency. Bleeding typically develops from 6 months to 1 year after completion of radiation therapy and is caused by friable mucosal angioectasias. Although many approaches to controlling bleeding from chronic radiation proctopathy have been attempted, ranging from topical enema formulations to surgical diversion of the rectum, endoscopic coagulation therapy remains the most effective. This review provides the background issues surrounding the development of chronic bleeding radiation proctopathy and focuses on endoscopic methods of treatment.

Original languageEnglish (US)
Pages (from-to)36-40
Number of pages5
JournalJournal of clinical gastroenterology
Volume27
Issue number1
DOIs
StatePublished - Aug 13 1998

Keywords

  • Lower gastrointestinal bleeding
  • Radiation
  • Vascular ectasias

ASJC Scopus subject areas

  • Gastroenterology

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