Endoscopic therapy for early esophageal cancer and premalignant lesions in barrett's esophagus

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The major medical consequence of Barrett's esophagus (BE) is the potential risk of development of esophageal adenocarcinoma. It is the management of this cancer risk and early cancers that is the focus of endoscopic therapies. As the risk of cancer increases, the types of endoscopic therapies that can be applied become more invasive. These therapies involve removal of the esophageal mucosa and portions of the submucosa, thermal therapies to cauterize the neoplastic tissue, and the use of photochemical therapies that cause localized tissue necrosis. Case series suggest that these treatments are effective and in selected patients can be used in lieu of surgery or in patients who are not surgical candidates. However, randomized controlled trials are lacking.

Original languageEnglish (US)
Title of host publicationEndoscopic Oncology
Subtitle of host publicationGastrointestinal Endoscopy and Cancer Management
PublisherHumana Press
Pages43-51
Number of pages9
ISBN (Print)158829532X, 9781588295323
DOIs
StatePublished - Dec 1 2006

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prasad, G. A., & Wang, K. K. (2006). Endoscopic therapy for early esophageal cancer and premalignant lesions in barrett's esophagus. In Endoscopic Oncology: Gastrointestinal Endoscopy and Cancer Management (pp. 43-51). Humana Press. https://doi.org/10.1007/978-1-59745-172-7_5