Endoscopic sleeve gastroplasty: A potential endoscopic alternative to surgical sleeve gastrectomy for treatment of obesity

Barham K. Abu Dayyeh, Elizabeth Rajan, Christopher J. Gostout

Research output: Contribution to journalArticle

84 Citations (Scopus)

Abstract

Background: Obesity and its associated conditions, including type 2 diabetes and cardiovascular disease, have reached epidemic proportions. High-efficacy, high-risk surgical approaches are unlikely to meet the increasing burden of disease. Emerging endoscopic technologies have opened the door for endoscopic approaches to reproduce many of the benefits of GI weight loss surgery and thereby contribute to the effective treatment of obesity and its associated disorders. Objective: To demonstrate the technical feasibility of transoral endoscopic gastric volume reduction with an endoscopic suturing device in a fashion similar to sleeve gastrectomy for the treatment of obesity. Design: Single-center, pilot feasibility study. Patients: Four human subjects with obesity. Interventions: Transoral sleeve gastroplasty. Main Outcome Measurements: Technical feasibility. Results: We successfully used an endoscopic free-hand suturing system in 4 subjects, thus demonstrating the technical feasibility of a novel technique to mimic the anatomic manipulations created by surgical sleeve gastrectomy endoscopically. Limitations: Pilot feasibility study with small number of subjects. Conclusions: Endoscopic sleeve gastroplasty for treatment of obesity is feasible.

Original languageEnglish (US)
Pages (from-to)530-535
Number of pages6
JournalGastrointestinal Endoscopy
Volume78
Issue number3
DOIs
StatePublished - Sep 2013

Fingerprint

Gastroplasty
Gastrectomy
Obesity
Feasibility Studies
Therapeutics
Type 2 Diabetes Mellitus
Weight Loss
Stomach
Cardiovascular Diseases
Hand
Technology
Equipment and Supplies

ASJC Scopus subject areas

  • Gastroenterology
  • Radiology Nuclear Medicine and imaging

Cite this

Endoscopic sleeve gastroplasty : A potential endoscopic alternative to surgical sleeve gastrectomy for treatment of obesity. / Abu Dayyeh, Barham K.; Rajan, Elizabeth; Gostout, Christopher J.

In: Gastrointestinal Endoscopy, Vol. 78, No. 3, 09.2013, p. 530-535.

Research output: Contribution to journalArticle

Abu Dayyeh, Barham K. ; Rajan, Elizabeth ; Gostout, Christopher J. / Endoscopic sleeve gastroplasty : A potential endoscopic alternative to surgical sleeve gastrectomy for treatment of obesity. In: Gastrointestinal Endoscopy. 2013 ; Vol. 78, No. 3. pp. 530-535.
@article{587965a4894447468b35829822eed781,
title = "Endoscopic sleeve gastroplasty: A potential endoscopic alternative to surgical sleeve gastrectomy for treatment of obesity",
abstract = "Background: Obesity and its associated conditions, including type 2 diabetes and cardiovascular disease, have reached epidemic proportions. High-efficacy, high-risk surgical approaches are unlikely to meet the increasing burden of disease. Emerging endoscopic technologies have opened the door for endoscopic approaches to reproduce many of the benefits of GI weight loss surgery and thereby contribute to the effective treatment of obesity and its associated disorders. Objective: To demonstrate the technical feasibility of transoral endoscopic gastric volume reduction with an endoscopic suturing device in a fashion similar to sleeve gastrectomy for the treatment of obesity. Design: Single-center, pilot feasibility study. Patients: Four human subjects with obesity. Interventions: Transoral sleeve gastroplasty. Main Outcome Measurements: Technical feasibility. Results: We successfully used an endoscopic free-hand suturing system in 4 subjects, thus demonstrating the technical feasibility of a novel technique to mimic the anatomic manipulations created by surgical sleeve gastrectomy endoscopically. Limitations: Pilot feasibility study with small number of subjects. Conclusions: Endoscopic sleeve gastroplasty for treatment of obesity is feasible.",
author = "{Abu Dayyeh}, {Barham K.} and Elizabeth Rajan and Gostout, {Christopher J.}",
year = "2013",
month = "9",
doi = "10.1016/j.gie.2013.04.197",
language = "English (US)",
volume = "78",
pages = "530--535",
journal = "Gastrointestinal Endoscopy",
issn = "0016-5107",
publisher = "Mosby Inc.",
number = "3",

}

TY - JOUR

T1 - Endoscopic sleeve gastroplasty

T2 - A potential endoscopic alternative to surgical sleeve gastrectomy for treatment of obesity

AU - Abu Dayyeh, Barham K.

AU - Rajan, Elizabeth

AU - Gostout, Christopher J.

PY - 2013/9

Y1 - 2013/9

N2 - Background: Obesity and its associated conditions, including type 2 diabetes and cardiovascular disease, have reached epidemic proportions. High-efficacy, high-risk surgical approaches are unlikely to meet the increasing burden of disease. Emerging endoscopic technologies have opened the door for endoscopic approaches to reproduce many of the benefits of GI weight loss surgery and thereby contribute to the effective treatment of obesity and its associated disorders. Objective: To demonstrate the technical feasibility of transoral endoscopic gastric volume reduction with an endoscopic suturing device in a fashion similar to sleeve gastrectomy for the treatment of obesity. Design: Single-center, pilot feasibility study. Patients: Four human subjects with obesity. Interventions: Transoral sleeve gastroplasty. Main Outcome Measurements: Technical feasibility. Results: We successfully used an endoscopic free-hand suturing system in 4 subjects, thus demonstrating the technical feasibility of a novel technique to mimic the anatomic manipulations created by surgical sleeve gastrectomy endoscopically. Limitations: Pilot feasibility study with small number of subjects. Conclusions: Endoscopic sleeve gastroplasty for treatment of obesity is feasible.

AB - Background: Obesity and its associated conditions, including type 2 diabetes and cardiovascular disease, have reached epidemic proportions. High-efficacy, high-risk surgical approaches are unlikely to meet the increasing burden of disease. Emerging endoscopic technologies have opened the door for endoscopic approaches to reproduce many of the benefits of GI weight loss surgery and thereby contribute to the effective treatment of obesity and its associated disorders. Objective: To demonstrate the technical feasibility of transoral endoscopic gastric volume reduction with an endoscopic suturing device in a fashion similar to sleeve gastrectomy for the treatment of obesity. Design: Single-center, pilot feasibility study. Patients: Four human subjects with obesity. Interventions: Transoral sleeve gastroplasty. Main Outcome Measurements: Technical feasibility. Results: We successfully used an endoscopic free-hand suturing system in 4 subjects, thus demonstrating the technical feasibility of a novel technique to mimic the anatomic manipulations created by surgical sleeve gastrectomy endoscopically. Limitations: Pilot feasibility study with small number of subjects. Conclusions: Endoscopic sleeve gastroplasty for treatment of obesity is feasible.

UR - http://www.scopus.com/inward/record.url?scp=84882267155&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84882267155&partnerID=8YFLogxK

U2 - 10.1016/j.gie.2013.04.197

DO - 10.1016/j.gie.2013.04.197

M3 - Article

C2 - 23711556

AN - SCOPUS:84882267155

VL - 78

SP - 530

EP - 535

JO - Gastrointestinal Endoscopy

JF - Gastrointestinal Endoscopy

SN - 0016-5107

IS - 3

ER -