Endoscopic Imaging for the Detection of Esophageal Dysplasia and Carcinoma

Muhammad W. Shahid, Michael B. Wallace

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

Numerous endoscopic imaging modalities have been developed and introduced into clinical practice to enhance diagnostic capabilities. In the past, detection of dysplasia and carcinoma of the esophagus has been dependent on biopsies taken during standard white-light endoscopy. Recent important developments in biophonotics have improved visualization of these subtle lesions sufficiently for cellular details to be seen in vivo during endoscopy. These improvements allow diagnosis to be made in gastrointestinal endoscopy units, thereby avoiding the cost, risk, and time delay involved in tissue biopsy and resection. Chromoendoscopy, narrow-band imaging, high-yield white-light endoscopy, Fujinon intelligent color enhancement, and point enhancement such as confocal laser endomicroscopy are examples of enhanced imaging technologies that are being used in daily practice. This article reviews endoscopic-based imaging techniques for the detection of esophageal dysplasia and carcinoma from the perspective of routine clinical practice.

Original languageEnglish (US)
Pages (from-to)11-24
Number of pages14
JournalGastrointestinal Endoscopy Clinics of North America
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2010

Keywords

  • Auto-fluorescence
  • Barrett's
  • Chromoendoscopy
  • Confocal
  • Endoscopy
  • NBI
  • OCT
  • Spectroscopy

ASJC Scopus subject areas

  • Gastroenterology

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