Endoscopic esophageal cancer survey in the western part of the Caspian Littoral

F. Saidi, R. Malekzadeh, M. Sotoudeh, M. H. Derakhshan, M. J. Farahvash, A. Yazdanbod, Sh Merat, J. Mikaeli, R. Sotoudehmanesh, S. Nasseri-Moghadam, A. Majidpour, S. Arshi, B. Abedi-Ardakani, A. Yoonessi, F. Sadr, A. Sepehr, D. Fleischer, S. Fahimi

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

After a hiatus of 30 years an attempt is now being made to re-assess the previously reported very high esophageal cancer incidence rates in the Caspian Littoral. The extraordinarily high incidence rates found in the estern side of the Littoral, were re-confirmed five years ago for the Turkoman region, using esophageal balloon cytology supplemented by esophagoscopy of suspected cases. The focus this time was on the Ardabil province in the western side of the Caspian Littoral, where the rates reported 30 years ago were moderately high. A pilot chromoendoscopic screening program was scheduled for 650 asymptomatic adults from a randomly selected part of the city of Ardabil and adjoining villages, to evaluate the overall patterns of esophageal disease and to establish the utility of endoscopy as an esophageal cancer screening tool. 504 healthy volunteers, giving a compliance rate of 77.5%, submitted to esophagogastroscopy without any mishaps. Contrary to expectation, no dysplasia or esophageal cancer was found in 914 satisfactory biopsy specimens. Total absence of esophageal cancer or precursor dysplastic changes in the surveyed population in the western part of the Caspian Littoral was at variance with the cancer registry findings of three decades ago for the western part of the Littoral. A plausible explanation could be the improved socio-economic conditions and life style changes which have taken place in the recent past all along the Caspian Littoral, except in the Turkoman Plain.

Original languageEnglish (US)
Pages (from-to)214-218
Number of pages5
JournalDiseases of the Esophagus
Volume15
Issue number3
DOIs
StatePublished - 2002
Externally publishedYes

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Esophageal Neoplasms
Esophageal Diseases
Esophagoscopy
Incidence
Early Detection of Cancer
Endoscopy
Cell Biology
Registries
Life Style
Healthy Volunteers
Economics
Biopsy
Surveys and Questionnaires
Population
Neoplasms

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Saidi, F., Malekzadeh, R., Sotoudeh, M., Derakhshan, M. H., Farahvash, M. J., Yazdanbod, A., ... Fahimi, S. (2002). Endoscopic esophageal cancer survey in the western part of the Caspian Littoral. Diseases of the Esophagus, 15(3), 214-218. https://doi.org/10.1046/j.1442-2050.2002.00250.x

Endoscopic esophageal cancer survey in the western part of the Caspian Littoral. / Saidi, F.; Malekzadeh, R.; Sotoudeh, M.; Derakhshan, M. H.; Farahvash, M. J.; Yazdanbod, A.; Merat, Sh; Mikaeli, J.; Sotoudehmanesh, R.; Nasseri-Moghadam, S.; Majidpour, A.; Arshi, S.; Abedi-Ardakani, B.; Yoonessi, A.; Sadr, F.; Sepehr, A.; Fleischer, D.; Fahimi, S.

In: Diseases of the Esophagus, Vol. 15, No. 3, 2002, p. 214-218.

Research output: Contribution to journalArticle

Saidi, F, Malekzadeh, R, Sotoudeh, M, Derakhshan, MH, Farahvash, MJ, Yazdanbod, A, Merat, S, Mikaeli, J, Sotoudehmanesh, R, Nasseri-Moghadam, S, Majidpour, A, Arshi, S, Abedi-Ardakani, B, Yoonessi, A, Sadr, F, Sepehr, A, Fleischer, D & Fahimi, S 2002, 'Endoscopic esophageal cancer survey in the western part of the Caspian Littoral', Diseases of the Esophagus, vol. 15, no. 3, pp. 214-218. https://doi.org/10.1046/j.1442-2050.2002.00250.x
Saidi F, Malekzadeh R, Sotoudeh M, Derakhshan MH, Farahvash MJ, Yazdanbod A et al. Endoscopic esophageal cancer survey in the western part of the Caspian Littoral. Diseases of the Esophagus. 2002;15(3):214-218. https://doi.org/10.1046/j.1442-2050.2002.00250.x
Saidi, F. ; Malekzadeh, R. ; Sotoudeh, M. ; Derakhshan, M. H. ; Farahvash, M. J. ; Yazdanbod, A. ; Merat, Sh ; Mikaeli, J. ; Sotoudehmanesh, R. ; Nasseri-Moghadam, S. ; Majidpour, A. ; Arshi, S. ; Abedi-Ardakani, B. ; Yoonessi, A. ; Sadr, F. ; Sepehr, A. ; Fleischer, D. ; Fahimi, S. / Endoscopic esophageal cancer survey in the western part of the Caspian Littoral. In: Diseases of the Esophagus. 2002 ; Vol. 15, No. 3. pp. 214-218.
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AU - Farahvash, M. J.

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