Endoscopic and Radiographic Assessment of Crohn's Disease

Badr Al-Bawardy, Stephanie L. Hansel, Jeff L. Fidler, John M. Barlow, David H. Bruining

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Crohn's disease is a chronic inflammatory disorder that can progress to obstructive and penetrating complications. Although clinical symptoms are an important component of therapy, they correlate poorly with objective measures of inflammation. The treatment targets have evolved from clinical improvement only to the addition of more objective measures, such as endoscopic mucosal healing and radiologic response, which have been associated with favorable long-term outcomes, including reduced hospitalizations, surgeries, and need for corticosteroids. There are multiple endoscopic and radiologic scoring systems that can aid in quantifying disease activity and response to therapy. These modalities and scoring tools are discussed in this article.

Original languageEnglish (US)
Pages (from-to)493-513
Number of pages21
JournalGastroenterology Clinics of North America
Volume46
Issue number3
DOIs
StatePublished - Sep 1 2017

Keywords

  • Computed tomography
  • Crohn's disease
  • Endoscopy
  • Enterography
  • MRI
  • Mucosal healing
  • Ultrasound

ASJC Scopus subject areas

  • Gastroenterology

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