Endocytosis of calcium oxalate crystals and proliferation of renal tubular epithelial cells in a patient with type 1 primary hyperoxaluria

John C Lieske, B. H. Spargo, F. G. Toback

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

A patient with primary hyperoxaluria who received a liver-kidney transplant is presented. A postoperative renal biopsy showed apparent tubular cell endocytosis of calcium oxalate crystals and cell proliferation, indicating that renal epithelial cells do not perceive urinary crystals as inert. Such cellular responses to crystals may have a role in nephrolithiasis.

Original languageEnglish (US)
Pages (from-to)1517-1519
Number of pages3
JournalJournal of Urology
Volume148
Issue number5 I
StatePublished - 1992
Externally publishedYes

Fingerprint

Calcium Oxalate
Endocytosis
Epithelial Cells
Kidney
Primary Hyperoxaluria
Nephrolithiasis
Cell Proliferation
Transplants
Biopsy
Liver
Primary hyperoxaluria type 1

Keywords

  • calcium oxalate
  • hyperoxaluria
  • kidney transplantation
  • liver transplantation
  • urinary calculi

ASJC Scopus subject areas

  • Urology

Cite this

Endocytosis of calcium oxalate crystals and proliferation of renal tubular epithelial cells in a patient with type 1 primary hyperoxaluria. / Lieske, John C; Spargo, B. H.; Toback, F. G.

In: Journal of Urology, Vol. 148, No. 5 I, 1992, p. 1517-1519.

Research output: Contribution to journalArticle

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