Endocrine regulation of ageing

Stephen J Russell, C. Ronald Kahn

Research output: Contribution to journalArticle

255 Citations (Scopus)

Abstract

Over the past 15 years it has become clear that mutations in genes that regulate endocrine signalling pathways can prolong lifespan. Lifespan can be increased by altered endocrine signalling in a group of cells or a single tissue, which indicates that crosstalk between tissues functions to coordinate ageing of the organism. These endocrine pathways might serve as targets for the manipulation of the ageing process and prevention of age-related diseases.

Original languageEnglish (US)
Pages (from-to)681-691
Number of pages11
JournalNature Reviews Molecular Cell Biology
Volume8
Issue number9
DOIs
StatePublished - Sep 2007
Externally publishedYes

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Mutation
Genes

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Endocrine regulation of ageing. / Russell, Stephen J; Kahn, C. Ronald.

In: Nature Reviews Molecular Cell Biology, Vol. 8, No. 9, 09.2007, p. 681-691.

Research output: Contribution to journalArticle

Russell, Stephen J ; Kahn, C. Ronald. / Endocrine regulation of ageing. In: Nature Reviews Molecular Cell Biology. 2007 ; Vol. 8, No. 9. pp. 681-691.
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