Employment Status as an Indicator of Recovery and Function One Year after Hematopoietic Stem Cell Transplantation

Eleshia J. Morrison, Shawna L Ehlers, Carrie A. Bronars, Christi Ann Patten, Tabetha A. Brockman, James R Cerhan, William Hogan, Shahrukh K. Hashmi, Dennis A. Gastineau

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Employment after hematopoietic stem cell transplantation (HSCT) is an indicator of post-transplantation recovery and function, with economic and social implications. As survival rates for HSCT continue to improve, greater emphasis can be placed on factors affecting the quality of post-transplantation survival, including the ability to resume employment. A sample of recipients of autologous or allogeneic HSCT was accrued (n = 1000) to complete a longitudinal lifestyle survey before transplantation and at 1 year after transplantation. The present study examines associations between employment and patient characteristics, disease variables, illness status, and quality of life among 1-year survivors (n = 702). Participants had a mean age of 55 years (range, 18 to 78) and were predominately male (59.7%), married/partnered (77.1%), and non-Hispanic Caucasian (89.5%); most (79.4%) had received autologous transplantation. Of the 690 participants reporting some form of employment before illness diagnosis, 62.4% had returned to work by 1 year after HSCT. Full-time employment at 1 year after HSCT was significantly associated with remission of illness, improved illness, fewer post-transplantation hospitalizations, less fatigue and pain, higher quality of life, and higher rating of perceived health. Those unemployed because of their health reported the highest rates of fatigue and pain and lowest quality of life, and they were most likely to report poor perceived health. These findings highlight work reintegration as an important outcome and marker of survivors’ overall adjustment after transplantation. Identifying factors affecting post-transplantation employment offers opportunities for behavioral interventions to target modifiable risk factors to optimize post-transplantation survivorship, inclusive of increased rates of return to work and decreased rates of associated disability.

Original languageEnglish (US)
Pages (from-to)1690-1695
Number of pages6
JournalBiology of Blood and Marrow Transplantation
Volume22
Issue number9
DOIs
StatePublished - Sep 1 2016

Fingerprint

Hematopoietic Stem Cell Transplantation
Recovery of Function
Transplantation
Quality of Life
Fatigue
Survivors
Health
Survival Rate
Social Adjustment
Pain
Aptitude
Return to Work
Autologous Transplantation
Longitudinal Studies
Life Style
Hospitalization
Economics
Survival

Keywords

  • Disease status
  • Employment
  • Hematopoietic stem cell transplantation
  • Physical symptoms
  • Quality of life
  • Transplantation survivorship

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Employment Status as an Indicator of Recovery and Function One Year after Hematopoietic Stem Cell Transplantation. / Morrison, Eleshia J.; Ehlers, Shawna L; Bronars, Carrie A.; Patten, Christi Ann; Brockman, Tabetha A.; Cerhan, James R; Hogan, William; Hashmi, Shahrukh K.; Gastineau, Dennis A.

In: Biology of Blood and Marrow Transplantation, Vol. 22, No. 9, 01.09.2016, p. 1690-1695.

Research output: Contribution to journalArticle

Morrison, Eleshia J. ; Ehlers, Shawna L ; Bronars, Carrie A. ; Patten, Christi Ann ; Brockman, Tabetha A. ; Cerhan, James R ; Hogan, William ; Hashmi, Shahrukh K. ; Gastineau, Dennis A. / Employment Status as an Indicator of Recovery and Function One Year after Hematopoietic Stem Cell Transplantation. In: Biology of Blood and Marrow Transplantation. 2016 ; Vol. 22, No. 9. pp. 1690-1695.
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