Empirical evaluation of the generalizability of the sample from the multimodal treatment study for ADHD

Jack Stevens, Kelly Kelleher, Joel Greenhouse, Guanmin Chen, Huiyun Xiang, Eloise Kaizar, Peter S. Jensen, L. Eugene Arnold

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Randomized controlled trials (RCTs) are criticized for the questionable generalizability of their patient samples to real world populations. This study compared the demographic and clinical characteristics of children from the Multimodal Treatment Study of Children with ADHD (MTA) to those from the NIMH Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) Study and the National Health and Nutrition Examination Survey (NHANES). On the whole, we found no compelling evidence against the representativeness of the MTA sample, but the limited power from MECA and NHANES may have lead to noteworthy differences between datasets being statistically nonsignificant.

Original languageEnglish (US)
Pages (from-to)221-232
Number of pages12
JournalAdministration and Policy in Mental Health and Mental Health Services Research
Volume34
Issue number3
DOIs
StatePublished - May 1 2007

Keywords

  • ADHD
  • External validity
  • Generalizability

ASJC Scopus subject areas

  • Phychiatric Mental Health
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health

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