Emotional Problems, Quality of Life, and Symptom Burden in Patients With Lung Cancer

Eleshia J. Morrison, Paul J. Novotny, Jeff A Sloan, Ping Yang, Christi Ann Patten, Kathryn J Ruddy, Matthew M Clark

Research output: Contribution to journalArticle

30 Scopus citations


Objectives: Lung cancer is associated with a greater symptom burden than other cancers, yet little is known about the prevalence of emotional problems and how emotional problems may be related to the physical symptom burden and quality of life in newly diagnosed patients with lung cancer. This study aimed to identify the patient and disease characteristics of patients with lung cancer experiencing emotional problems and to examine how emotional problems relate to quality of life and symptom burden. Patients and Methods: A total of 2205 newly diagnosed patients with lung cancer completed questionnaires on emotional problems, quality of life, and symptom burden. Results: Emotional problems at diagnosis were associated with younger age, female gender, current cigarette smoking, current employment, advanced lung cancer disease, surgical or chemotherapy treatment, and a lower Eastern Cooperative Oncology Group performance score. Additionally, strong associations were found between greater severity of emotional problems, lower quality of life, and greater symptom burden. Conclusion: Certain characteristics place patients with lung cancer at greater risk for emotional problems, which are associated with a reduced quality of life and greater symptom burden. Assessment of the presence of emotional problems at the time of lung cancer diagnosis provides the opportunity to offer tailored strategies for managing negative mood, and for improving the quality of life and symptom burden management of patients with lung cancer.

Original languageEnglish (US)
JournalClinical Lung Cancer
StateAccepted/In press - Jul 18 2016


  • Newly diagnosed cancer
  • Patient/disease characteristics
  • Physical symptom burden
  • Psychological distress
  • QOL

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

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