Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma

Hiroaki Haga; Irene Yan; Kenji Takahashi; Joseph Wood; Tushar Patel

doi:10.3727/105221614X13919976902174

Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma

Hiroaki Haga, Irene Yan, Kenji Takahashi, Joseph Wood, Tushar Patel

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.

Original language	English (US)
Pages (from-to)	93-99
Number of pages	7
Journal	Gene expression
Volume	16
Issue number	2
DOIs	https://doi.org/10.3727/105221614X13919976902174
State	Published - Apr 2014

Keywords

Biliary tract cancers
Cell death
Cell proliferation
Epithelial-mesenchymal transition
Noncoding RNA

ASJC Scopus subject areas

Molecular Biology
Genetics

Access to Document

10.3727/105221614X13919976902174

Cite this

@article{ca67e920c0e44428b33c6a1d483d41d8,

title = "Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma",

abstract = "The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.",

keywords = "Biliary tract cancers, Cell death, Cell proliferation, Epithelial-mesenchymal transition, Noncoding RNA",

author = "Hiroaki Haga and Irene Yan and Kenji Takahashi and Joseph Wood and Tushar Patel",

year = "2014",

month = apr,

doi = "10.3727/105221614X13919976902174",

language = "English (US)",

volume = "16",

pages = "93--99",

journal = "Gene Expression",

issn = "1052-2166",

publisher = "Cognizant Communication Corporation",

number = "2",

}

TY - JOUR

T1 - Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma

AU - Haga, Hiroaki

AU - Yan, Irene

AU - Takahashi, Kenji

AU - Wood, Joseph

AU - Patel, Tushar

PY - 2014/4

Y1 - 2014/4

N2 - The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.

AB - The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.

KW - Biliary tract cancers

KW - Cell death

KW - Cell proliferation

KW - Epithelial-mesenchymal transition

KW - Noncoding RNA

UR - http://www.scopus.com/inward/record.url?scp=84900565779&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84900565779&partnerID=8YFLogxK

U2 - 10.3727/105221614X13919976902174

DO - 10.3727/105221614X13919976902174

M3 - Review article

C2 - 24801170

AN - SCOPUS:84900565779

VL - 16

SP - 93

EP - 99

JO - Gene Expression

JF - Gene Expression

SN - 1052-2166

IS - 2

ER -

Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this