Abstract
The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 93-99 |
| Number of pages | 7 |
| Journal | Gene Expression |
| Volume | 16 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2014 |
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Keywords
- Biliary tract cancers
- Cell death
- Cell proliferation
- Epithelial-mesenchymal transition
- Noncoding RNA
ASJC Scopus subject areas
- Genetics
- Molecular Biology
Cite this
Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma. / Haga, Hiroaki; Yan, Irene; Takahashi, Kenji; Wood, Joseph; Patel, Tushar C.
In: Gene Expression, Vol. 16, No. 2, 2014, p. 93-99.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma
AU - Haga, Hiroaki
AU - Yan, Irene
AU - Takahashi, Kenji
AU - Wood, Joseph
AU - Patel, Tushar C
PY - 2014
Y1 - 2014
N2 - The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.
AB - The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.
KW - Biliary tract cancers
KW - Cell death
KW - Cell proliferation
KW - Epithelial-mesenchymal transition
KW - Noncoding RNA
UR - http://www.scopus.com/inward/record.url?scp=84900565779&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84900565779&partnerID=8YFLogxK
U2 - 10.3727/105221614X13919976902174
DO - 10.3727/105221614X13919976902174
M3 - Article
C2 - 24801170
AN - SCOPUS:84900565779
VL - 16
SP - 93
EP - 99
JO - Gene Expression
JF - Gene Expression
SN - 1052-2166
IS - 2
ER -