Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma

Hiroaki Haga; Irene Yan; Kenji Takahashi; Joseph Wood; Tushar Patel

doi:10.3727/105221614X13919976902174

Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma

Hiroaki Haga, Irene Yan, Kenji Takahashi, Joseph Wood, Tushar Patel

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.

Original language	English (US)
Pages (from-to)	93-99
Number of pages	7
Journal	Gene expression
Volume	16
Issue number	2
DOIs	https://doi.org/10.3727/105221614X13919976902174
State	Published - Apr 2014

Keywords

Biliary tract cancers
Cell death
Cell proliferation
Epithelial-mesenchymal transition
Noncoding RNA

ASJC Scopus subject areas

Molecular Biology
Genetics

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abstract = "The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.",

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