Emerging insights into the role of MicroRNAs in the pathogenesis of cholangiocarcinoma

Hiroaki Haga, Irene Yan, Kenji Takahashi, Joseph Wood, Tushar Patel

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

The microRNAs (miRNAs) are small noncoding RNAs that are potent regulators of gene expression and can regulate several diverse biological functions. This minireview provides an overview of recent studies that have examined the role and involvement of miRNAs in cholangiocarcinomas. These studies provide evidence for deregulated expression of miRNA and are providing new insights into the potential contribution of these in the pathogenesis of cholangiocarcinoma.

Original languageEnglish (US)
Pages (from-to)93-99
Number of pages7
JournalGene expression
Volume16
Issue number2
DOIs
StatePublished - Apr 2014

Keywords

  • Biliary tract cancers
  • Cell death
  • Cell proliferation
  • Epithelial-mesenchymal transition
  • Noncoding RNA

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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