Embolic Protection Devices in Patients with Renal Artery Stenosis with Chronic Renal Insufficiency

A Clinical Study

Sanjay Misra, Manuel T. Gomes, Verghese Mathew, Gregory W. Barsness, Stephen C Textor, Haraldur Bjarnason, Michael A. McKusick

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: To present clinical outcomes with the use of embolic protection devices (EPDs) and renal artery stents in patients with chronic renal insufficiency (CRI) and renal artery stenosis (RAS). Materials and Methods: A retrospective study was conducted in 23 patients with RAS and CRI who were treated with renal artery stent placement with an EPD. Follow-up data were obtained through medical records. Results: In 23 patients (18 men; 78%) with an average age of 69.4 years ± 11 (range, 46-86 y), 32 renal arteries were treated for worsening renal function (n = 17; 74%) or uncontrolled hypertension and worsening renal function (n = 6; 26%). Nine FilterWire EZ devices were used in eight patients (35%) and 17 SpideRX devices were used in 15 patients (65%). The average follow-up was 8 months ± 5. After the stent procedure, the mean systolic blood pressure decreased significantly (P < .05) whereas the diastolic pressure remained unchanged. There was a significant increase in the mean estimated glomerular filtration rate from 32.9 mL/min ± 12.9 at baseline to 41.3 mL/min ± 13.7 at last follow-up (P < .05). In 96% of patients, there was improvement or stabilization of kidney function. In six of the 17 SpideRX devices (35%), macroscopically evident embolic material was observed in the device after stent placement. There were two minor and two major complications. Conclusions: Renal artery stent placement combined with the use of a SpideRX or FilterWire EZ device is associated with an good clinical outcome with a reasonable safety profile.

Original languageEnglish (US)
Pages (from-to)1639-1645
Number of pages7
JournalJournal of Vascular and Interventional Radiology
Volume19
Issue number11
DOIs
StatePublished - Nov 2008

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Embolic Protection Devices
Renal Artery Obstruction
Chronic Renal Insufficiency
Stents
Renal Artery
Equipment and Supplies
Blood Pressure
Kidney
Renal Hypertension
Glomerular Filtration Rate
Medical Records
Clinical Studies
Retrospective Studies
Safety

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Embolic Protection Devices in Patients with Renal Artery Stenosis with Chronic Renal Insufficiency : A Clinical Study. / Misra, Sanjay; Gomes, Manuel T.; Mathew, Verghese; Barsness, Gregory W.; Textor, Stephen C; Bjarnason, Haraldur; McKusick, Michael A.

In: Journal of Vascular and Interventional Radiology, Vol. 19, No. 11, 11.2008, p. 1639-1645.

Research output: Contribution to journalArticle

Misra, Sanjay ; Gomes, Manuel T. ; Mathew, Verghese ; Barsness, Gregory W. ; Textor, Stephen C ; Bjarnason, Haraldur ; McKusick, Michael A. / Embolic Protection Devices in Patients with Renal Artery Stenosis with Chronic Renal Insufficiency : A Clinical Study. In: Journal of Vascular and Interventional Radiology. 2008 ; Vol. 19, No. 11. pp. 1639-1645.
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