Electrophoretic deposition of porous hydroxyapatite scaffold

J. Ma, C. Wang, K. W. Peng

Research output: Contribution to journalArticle

140 Scopus citations

Abstract

Bioactive porous hydroxyapatite (HA) scaffold was fabricated using electrophoretic deposition (EPD) technique in the present work. Bulk HA scaffold was achieved by repeated deposition. The green scaffold was sintered at 1200°C to 82% of the theoretical density. Scanning electron microscopy examination and mercury porosimetry measurement have shown that the porosity remains interconnected and a range of pore size from several microns to hundreds of microns was obtained. X-ray diffraction analysis was performed and confirmed that there is no HA decomposition during the sintering process. Mechanical characterization has also shown that the EPD scaffold possesses excellent properties. Cell culturing experiment was carried out and the result shows that the scaffold bioactivity is not only dependent on the interconnectivity of the pores, but also the pore size.

Original languageEnglish (US)
Pages (from-to)3505-3510
Number of pages6
JournalBiomaterials
Volume24
Issue number20
DOIs
StatePublished - Sep 2003

Keywords

  • Bioactivity
  • Electrophoretic deposition
  • Hydroxyapatite
  • Interconnected porosity

ASJC Scopus subject areas

  • Bioengineering
  • Ceramics and Composites
  • Biophysics
  • Biomaterials
  • Mechanics of Materials

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