TY - JOUR
T1 - Electronic health records
T2 - Implications for drug discovery
AU - Yao, Lixia
AU - Zhang, Yiye
AU - Li, Yong
AU - Sanseau, Philippe
AU - Agarwal, Pankaj
PY - 2011/7
Y1 - 2011/7
N2 - Electronic health records (EHRs) have increased in popularity in many countries. Pushed by legal mandates, EHR systems have seen substantial progress recently, including increasing adoption of standards, improved medical vocabularies and enhancements in technical infrastructure for data sharing across healthcare providers. Although the progress is directly beneficial to patient care in a hospital or clinical setting, it can also aid drug discovery. In this article, we review three specific applications of EHRs in a drug discovery context: finding novel relationships between diseases, re-evaluating drug usage and discovering phenotype-genotype associations. We believe that in the near future EHR systems and related databases will impact significantly how we discover and develop safe and efficacious medicines.
AB - Electronic health records (EHRs) have increased in popularity in many countries. Pushed by legal mandates, EHR systems have seen substantial progress recently, including increasing adoption of standards, improved medical vocabularies and enhancements in technical infrastructure for data sharing across healthcare providers. Although the progress is directly beneficial to patient care in a hospital or clinical setting, it can also aid drug discovery. In this article, we review three specific applications of EHRs in a drug discovery context: finding novel relationships between diseases, re-evaluating drug usage and discovering phenotype-genotype associations. We believe that in the near future EHR systems and related databases will impact significantly how we discover and develop safe and efficacious medicines.
UR - http://www.scopus.com/inward/record.url?scp=79959710692&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959710692&partnerID=8YFLogxK
U2 - 10.1016/j.drudis.2011.05.009
DO - 10.1016/j.drudis.2011.05.009
M3 - Review article
C2 - 21624499
AN - SCOPUS:79959710692
SN - 1359-6446
VL - 16
SP - 594
EP - 599
JO - Drug Discovery Today
JF - Drug Discovery Today
IS - 13-14
ER -