Electroencephalography in Survivors of Cardiac Arrest: Comparing Pre- and Post-therapeutic Hypothermia Eras

Amy Z. Crepeau, Jeffrey W. Britton, Jennifer E. Fugate, Alejandro Rabinstein, Eelco F. Wijdicks

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Electroencephalography in the setting of hypothermia and anoxia has been studied in humans since the 1950s. Specific patterns after cardiac arrest have been associated with prognosis since the 1960s, with several prognostic rating scales developed in the second half of the twentieth century. In 2002, two pivotal clinical trials were published, demonstrating improved neurologic outcomes in patients treated with therapeutic hypothermia (TH) after cardiac arrest of shockable rhythms. In the following years, TH became the standard of care in these patients. During the same time period, the use of continuous EEG monitoring in critically ill patients increased, which led to the recognition of subclinical seizures occurring in patients after cardiac arrest. As a result of these changes, greater amounts of EEG data are being collected, and the significance of specific patterns is being re-explored. We review the current role of EEG for the identification of seizures and the estimation of prognosis after cardiac resuscitation.

Original languageEnglish (US)
Pages (from-to)165-172
Number of pages8
JournalNeurocritical Care
Volume22
Issue number1
DOIs
StatePublished - 2015

Fingerprint

Induced Hypothermia
Heart Arrest
Survivors
Electroencephalography
Partial Epilepsy
Standard of Care
Hypothermia
Critical Illness
Resuscitation
Nervous System
Seizures
Clinical Trials

Keywords

  • Cardiac arrest
  • Clinical neurophysiology
  • EEG
  • Prognosis
  • Therapeutic hypothermia

ASJC Scopus subject areas

  • Clinical Neurology
  • Critical Care and Intensive Care Medicine

Cite this

Electroencephalography in Survivors of Cardiac Arrest : Comparing Pre- and Post-therapeutic Hypothermia Eras. / Crepeau, Amy Z.; Britton, Jeffrey W.; Fugate, Jennifer E.; Rabinstein, Alejandro; Wijdicks, Eelco F.

In: Neurocritical Care, Vol. 22, No. 1, 2015, p. 165-172.

Research output: Contribution to journalArticle

Crepeau, Amy Z. ; Britton, Jeffrey W. ; Fugate, Jennifer E. ; Rabinstein, Alejandro ; Wijdicks, Eelco F. / Electroencephalography in Survivors of Cardiac Arrest : Comparing Pre- and Post-therapeutic Hypothermia Eras. In: Neurocritical Care. 2015 ; Vol. 22, No. 1. pp. 165-172.
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