Electroconvulsive therapy and newer modalities for the treatment of medication-refractory mental illness

Keith G. Rasmussen, Shirlene M. Sampson, Teresa A. Rummans

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Severe mental illnesses often remain chronic and refractory to medication, leading to substantial morbidity and mortality. For more than 60 years, electroconvulsive therapy has been the only nonpharmacological psychiatric procedure available to treat severe or medication-refractory major depressive disorder and other psychiatric conditions. Memory dysfunction remains the most serious adverse effect, and current research focuses on attempts to ameliorate this complication. Transcranial magnetic stimulation and vagus nerve stimulation, 2 new neuropsychiatric technologies, are emerging as possible additions to our therapeutic armamentarium. Besides providing therapeutic benefits, these 3 methods may help elucidate the pathophysiology of psychiatric illness.

Original languageEnglish (US)
Pages (from-to)552-556
Number of pages5
JournalMayo Clinic Proceedings
Volume77
Issue number6
StatePublished - 2002

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Electroconvulsive Therapy
Psychiatry
Vagus Nerve Stimulation
Transcranial Magnetic Stimulation
Major Depressive Disorder
Therapeutics
Technology
Morbidity
Mortality
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Electroconvulsive therapy and newer modalities for the treatment of medication-refractory mental illness. / Rasmussen, Keith G.; Sampson, Shirlene M.; Rummans, Teresa A.

In: Mayo Clinic Proceedings, Vol. 77, No. 6, 2002, p. 552-556.

Research output: Contribution to journalArticle

Rasmussen, Keith G. ; Sampson, Shirlene M. ; Rummans, Teresa A. / Electroconvulsive therapy and newer modalities for the treatment of medication-refractory mental illness. In: Mayo Clinic Proceedings. 2002 ; Vol. 77, No. 6. pp. 552-556.
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